CKD与CKM的相关性研究进展
Research Progress on the Correlation between CKD and CKM
DOI: 10.12677/acm.2026.1693131, PDF,    科研立项经费支持
作者: 戚玉莲, 赵欣蕾：昆明医科大学第二临床医学院，云南 昆明；杨 敏*：昆明医科大学第二附属医院肾脏内科，云南 昆明
关键词: 心血管–肾脏–代谢综合征；慢性肾脏病；心血管疾病；代谢疾病；Cardiovascular-Renal-Metabolic Syndrome； Chronic Kidney Disease； Cardiovascular Diseases； Metabolic Disease
摘要: 心血管–肾脏–代谢(CKM)综合征描述了代谢危险因素、慢性肾病和心血管系统之间复杂的病理生理相互作用，它是一种全身性疾病，会导致多器官功能障碍和心血管不良事件高发。CKM概念的提出为肾脏科的临床实践带来了新的视角和管理模式，肾脏作为CKM发生、发展的核心桥梁，在血流动力学调控、代谢调节和免疫反应中发挥着关键作用，应重视肾脏对心血管和代谢的慢性交互共损效应，深入了解其病理生理机制对早期预防和临床治疗具有重要意义。
Abstract: Cardiovascular-Kidney-Metabolic (CKM) syndrome describes the complex pathophysiological interactions between metabolic risk factors, chronic kidney disease, and the cardiovascular system. It is a systemic disease that leads to multi-organ dysfunction and a high incidence of adverse cardiovascular events. The introduction of the CKM concept has brought new perspectives and management models to clinical nephrology practice. The kidneys play a crucial role as the core bridge in the development of CKM, involved in hemodynamic regulation, metabolic regulation, and immune response. It is important to recognize the chronic reciprocal damage effects of the kidneys on the cardiovascular and metabolic systems, as understanding their pathophysiological mechanisms is significant for early prevention and clinical treatment.
文章引用：戚玉莲, 赵欣蕾, 杨敏. CKD与CKM的相关性研究进展[J]. 临床医学进展, 2026, 16(9): 1004-1012. https://doi.org/10.12677/acm.2026.1693131

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