2017至2025年环泊酚相关文献的计量学分析
Bibliometric Analysis of Ciprofol-Related Literature from 2017 to 2025
DOI: 10.12677/acm.2026.1693179, PDF,   
作者: 孙兴隆：青岛大学青岛医学院，山东 青岛；烟台毓璜顶医院麻醉科，山东 烟台；丁婉婷：烟台毓璜顶医院麻醉科，山东 烟台；山东医药大学第二临床医学院，山东 烟台；廖俊豪：青岛大学青岛医学院，山东 青岛；林宏程：武警部队山东省总队医院，山东 济南；马加海*：烟台毓璜顶医院麻醉科，山东 烟台
关键词: 环泊酚；文献计量学；可视化分析；研究热点；Ciprofol； Bibliometrics； Visualization Analysis； Research Hotspots
摘要: 目的：利用文献计量学与可视化分析方法，系统梳理新型静脉麻醉药环泊酚的研究现状、学术热点及演进趋势。方法：检索Web of Science核心合集数据库中建库至2025年12月31日发表的环泊酚相关文献。应用Excel 2010、GraphPad Prism 10、CiteSpace 6.4.R1和VOSviewer 1.6.20软件分析发文量、国家/地区、机构、期刊、作者、关键词及共被引文献。结果：共纳入文献205篇。环泊酚研究始于2017年，2021年后进入快速增长期。发文量最多的国家是中国，发文量最多的机构是四川大学，发文量最多的期刊是Drug Design, Development and Therapy，发文量最多的作者是刘筱。关键词聚类及引文突现分析显示，研究热点已从早期药理学评价，逐步转向多药联合、不同手术类型及特殊人群的精细化应用。结论：环泊酚研究正处于快速发展阶段，中国研究力量占绝对主导，但国际合作不足。未来研究应聚焦特定手术和特殊人群的剂量优化、个体化多药协同策略及对患者远期预后的保护效应研究。
Abstract: Objective: To systematically analyze the research status, academic hotspots, and evolutionary trends of the novel intravenous anesthetic ciprofol using bibliometric and visualization methods. Methods: Articles related to ciprofol published from inception to December 31, 2025, were retrieved from the Web of Science Core Collection. Excel 2010, GraphPad Prism 10, CiteSpace 6.4.R1, and VOSviewer 1.6.20 were used to analyze publication volume, countries/regions, institutions, journals, authors, keywords, and co-cited references. Results: A total of 205 articles were included. Research on ciprofol began in 2017 and entered a rapid growth phase after 2021. China had the highest number of publications, Sichuan University was the most productive institution, Drug Design, Development and Therapy was the leading journal, and Liu Xiao was the most prolific author. Keyword clustering and citation burst analysis indicated that research hotspots have shifted from early pharmacological evaluation to multidrug combination, application in different surgical types, and refined use in special populations. Conclusion: Ciprofol research is in a phase of rapid development, with Chinese research forces playing a dominant role but international collaboration being insufficient. Future research should focus on dose optimization for specific surgical procedures and special populations, individualized multidrug combination strategies, and protective effects on long-term patient outcomes.
文章引用：孙兴隆, 丁婉婷, 廖俊豪, 林宏程, 马加海. 2017至2025年环泊酚相关文献的计量学分析[J]. 临床医学进展, 2026, 16(9): 1412-1426. https://doi.org/10.12677/acm.2026.1693179

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