腔内射频消融术治疗不同直径大隐静脉曲张的临床疗效评价

Evaluation of Clinical Efficacy of Endovascular Radiofrequency Ablation in the Treatment of Varices of Great Saphenous Veins of Different Diameters

摘要: 目的：本研究旨在比较在超声引导下射频消融导管治疗不同直径大隐静脉的有效性。方法：本研究回顾性分析2018年9月到2021年9月暨南大学附属第一医院收治的120例下肢静脉曲张患者(平均年龄58 ± 2.4岁)，根据大隐静脉不同直径分a (<12 mm)、b (≥12 mm)组，分别为87例、33例，行超声检查比较不同大隐静脉射频消融术术前术后12个月的直径变化及复通情况。结果a组术前术后12个月大隐静脉直径为8 ± 2.9 mm、5.1 ± 0.7 mm (P = 0.01)，b组术前术后12个月大隐静脉直径为12 ± 2.4 mm、6.7 ± 0.8 mm (P = 0.03)，a、b组术后12个月大隐静脉复通率无统计学差异(P = 0.285)。结论射频消融治疗大隐静脉疗效确切，大隐静脉直径未显示影响射频消融术疗效，仍需更多临床研究予以证实。

Abstract: Objectives: This study aimed to compare the efficacy of ultrasound-guided radiofrequency ablation catheters for the treatment of different diameters of the great saphenous vein. Methods: This study retrospectively analyzed 120 patients with varicose veins of lower extremities (average age 58 ± 2.4 years) admitted to the First Affiliated Hospital of Ji’nan University from September 2018 to September 2021. According to the different diameters of the great saphenous vein, they were divided into a (<12 mm; n = 87) and b (≥12 mm; n = 33) groups. Ultrasonography was performed to compare the diameter changes and recanalization of different great saphenous vein radiofrequency ablation before and after 12 months. Results: In group a, GSV diameter decreased from 8.0 ± 2.9 mm preoperatively to 5.1 ± 0.7 mm at 12 months (P = 0.01); in group b, it decreased from 12.0 ± 2.4 mm to 6.7 ± 0.8 mm (P = 0.03). The 12-month recanalization rate did not differ significantly between groups (P = 0.285). Conclusion: Radiofrequency ablation is effective in the treatment of the great saphenous vein, and the diameter of the great saphenous vein does not affect the efficacy of radiofrequency ablation, and more clinical studies are needed to confirm it.