慢性增殖型念珠菌性口炎1例报告

A Case Report of Chronic Hyperplastic Candidiasis

摘要: 念珠菌常定植于人的皮肤、口腔黏膜、胃肠道和泌尿生殖道，属条件致病真菌。慢性增殖型念珠菌性口炎的临床表现与口腔白斑病、红斑型扁平苔藓等白色角化性病损存在重叠，临床误诊、漏诊率较高。本病例报告对1例慢性增殖型念珠菌性口炎的病例进行分析，探讨诊断和治疗要点，为口腔医生临床诊治提供切入点。患者使用氟康唑联合碳酸氢钠含漱及制霉菌素抗真菌治疗，感染得到有效控制，临床转归满意。

Abstract: Candida is commonly colonized on human skin, oral mucosa, gastrointestinal tract, and genitourinary tract, and is an opportunistic pathogenic fungus. The clinical manifestations of chronic hyperplastic candidiasis overlap with white keratotic lesions such as oral leukoplakia and erythematous lichen planus, leading to a high rate of misdiagnosis and missed diagnosis. This case report analyzes a case of chronic hyperplastic candidiasis, exploring the key points of diagnosis and treatment, providing a reference for clinical diagnosis and treatment for dentists. The patient received antifungal treatment with fluconazole combined with sodium bicarbonate mouth rinse and nystatin, which effectively controlled the infection, with a satisfactory clinical outcome.