五黄散外敷联合头孢他啶对湿热下注型急性附睾炎的临床研究

Clinical Study on Externally Applied Wuhuang Powder Combined with Ceftazidime for Acute Epididymitis of Damp-Heat Pouring Downward Pattern

摘要: 目的：通过观察患者症状与相关指标的改善情况，评估五黄散外敷联合头孢他啶在湿热下注型急性附睾炎治疗中的临床疗效。方法：选取2023年8月至2025年1月在乌鲁木齐市中医医院泌尿外科收治的湿热下注型急性附睾炎患者80例，按随机数字表法分为试验组和对照组，各40例。两组均接受基础护理及抗菌治疗，对照组单用头孢他啶静脉滴注，试验组在此基础上加用五黄散外敷治疗，疗程10天。治疗前后分别评估视觉模拟疼痛评分(VAS)、附睾彩超径线、C反应蛋白(CRP)水平及临床疗效。结果：治疗后两组患者疼痛评分、CRP水平及附睾体积均明显下降(P < 0.05)，且试验组下降幅度显著大于对照组(P < 0.05)。试验组总有效率为92.5%，明显高于对照组的75.0% (P < 0.05)。联合治疗能更有效减轻局部红肿疼痛，促进炎症吸收和附睾功能恢复。结论：五黄散外敷联合头孢他啶能有效缓解湿热下注型急性附睾炎的疼痛与炎症反应，促进附睾恢复，具有良好的协同消肿、止痛与活血化瘀作用，为该病的临床治疗提供了可行且有益的方案。

Abstract: Objective: To evaluate the clinical efficacy of externally applied Wuhuang Powder combined with ceftazidime for acute epididymitis of damp‑heat pouring‑down pattern through observing improvements in patients’ symptoms and relevant indicators. Methods: Eighty patients diagnosed with acute epididymitis of damp‑heat pouring‑down pattern, admitted to the Department of Urology, Urumqi Hospital of Traditional Chinese Medicine between August 2023 and January 2025, were allocated to an experimental group and a control group (40 cases for each) by the random‑number‑table method. Both groups received basic nursing and antibacterial therapy. The control group received intravenous ceftazidime monotherapy, while the experimental group was additionally given external application of Wuhuang Powder on the basis of the above treatment. The treatment course lasted 10 days. Assessments including Visual Analogue Scale (VAS) pain scores, epididymal diameters on color Doppler ultrasound, C‑reactive protein (CRP) levels and overall clinical efficacy were performed before and after intervention. Results: Pain scores, CRP levels and epididymal volume decreased significantly in both groups after treatment (P < 0.05), and the decreasing ranges in the experimental group were significantly greater than those in the control group (P < 0.05). The total effective rate reached 92.5% in the experimental group, obviously higher than 75.0% of the control group (P < 0.05). Combined therapy can more effectively relieve local redness, swelling and pain, and promote inflammation absorption and epididymal function recovery. Conclusion: The combination of externally applied Wuhuang Powder and ceftazidime can effectively relieve pain and inflammatory responses in patients with acute epididymitis of damp‑heat pouring‑down pattern and promote epididymal recovery. It presents favorable synergistic effects of detumescence, analgesia and blood‑activating and stasis‑resolving, which provides a feasible and beneficial regimen for clinical treatment of this disease.