基于“治痿独取阳明”探究电针治疗经皮椎间孔镜术后下肢肌肉萎缩的疗效研究
Exploring the Efficacy of Electroacupuncture in Treating Lower Limb Muscle Atrophy after Percutaneous Endoscopic Lumbar Discectomy Based on the Principle of “Treating Weakness by Focusing on the Yangming Meridian”
DOI: 10.12677/tcm.2026.1511623, PDF,   
作者: 王 振, 宋寒冰*:黑龙江中医药大学研究生院,黑龙江 哈尔滨
关键词: 腰椎间盘突出症;术后康复;电针疗法;Lumbar Disc Herniation; Postoperative Rehabilitation; Electroacupuncture Therapy
摘要: 探究以“治痿独取阳明”理论为取穴原则,运用电针疗法联合康复训练治疗经皮椎间孔镜术后下肢肌肉萎缩的疗效。选取符合纳入标准的60名患者,采用随机数字表对患者进行随机分组,分为对照组和试验组,每组各取30名患者作为研究对象。其中对照组病例采用术后第2天常规针刺取穴治疗配合功能锻炼的治疗方案,试验组病例依据“治痿独取阳明”理论取穴进行针刺取穴,于术后第2天以取穴原则取穴并施行电针疗法配合功能锻炼的治疗方案。分别于术后第2天、术后1周、术后2周、术后1个月记录各组患者观察指标结果。结果显示,试验组治疗效果优于对照组,其中,试验组腰椎功能恢复较对照组明显,评分较对照组有所降低(P < 0.05);试验组关节活动度及下肢肌力恢复程度较对照组改善明显(P < 0.05);试验组改良Macnab评分改变明显,且略高于对照组(P < 0.05);试验组患者治疗后血清鸢尾素及骨钙素水平明显上升,较对照组提升明显(P < 0.05);试验组在治疗后下肢各肌肉的iEMG和RMS值提升,且变化程度高于对照组(P < 0.05);试验组患者在接受治疗之后下肢各肌肉厚度均有明显提升,且较对照组患者改善效果更佳(P < 0.05),各统计数据差异均有统计学意义。综上所述,以“治痿独取阳明”取穴原则配合电针治疗腰椎椎间孔镜术后下肢肌肉萎缩疗效较好,可改善患者术后康复状况,缓解患者不适症状,有助于患者的康复过程。
Abstract: To investigate the efficacy of using the theory of “treating weakness by focusing on the Yangming Meridian” as the acupoint selection principle, combined with electroacupuncture therapy and rehabilitation training, for treating lower limb muscle atrophy after percutaneous endoscopic lumbar discectomy. A total of 60 patients who met the inclusion criteria were selected and randomly divided into a control group and an experimental group using a random number table, with 30 patients in each group. The control group received conventional acupuncture at selected points starting on the second day after surgery, along with functional exercise. The experimental group received acupuncture at points selected according to the theory of “treating weakness by focusing on the Yangming Meridian”, with electroacupuncture therapy and functional exercise starting on the second day after surgery. Observation indicators were recorded on the second day, one week, two weeks, and one month after surgery. The results showed that the therapeutic effect in the experimental group was superior to that in the control group. Specifically, lumbar function recovery in the experimental group was significantly better than in the control group, with lower scores (P < 0.05). Joint mobility and lower limb muscle strength recovery improved more significantly in the experimental group than in the control group (P < 0.05). The modified Macnab scores in the experimental group showed significant improvement and were slightly higher than those in the control group (P < 0.05). Serum irisin and osteocalcin levels in the experimental group increased significantly after treatment, with a more pronounced rise compared to the control group (P < 0.05). The iEMG and RMS values of various lower limb muscles in the experimental group increased after treatment, with a greater degree of change than in the control group (P < 0.05). The thickness of each lower limb muscle in the experimental group significantly increased after treatment, with better improvement compared to the control group (P < 0.05). All statistical differences were statistically significant. In conclusion, the acupoint selection principle of “treating weakness by focusing on the Yangming Meridian” combined with electroacupuncture therapy is effective in treating lower limb muscle atrophy after percutaneous endoscopic lumbar discectomy. It improves postoperative rehabilitation, alleviates discomfort, and facilitates the recovery process.
文章引用:王振, 宋寒冰. 基于“治痿独取阳明”探究电针治疗经皮椎间孔镜术后下肢肌肉萎缩的疗效研究[J]. 中医学, 2026, 15(11): 54-65. https://doi.org/10.12677/tcm.2026.1511623

参考文献

[1] Yu, P., Mao, F., Chen, J., Ma, X., Dai, Y., Liu, G., et al. (2022) Characteristics and Mechanisms of Resorption in Lumbar Disc Herniation. Arthritis Research & Therapy, 24, Article No. 205.
https://doi.org/10.1186/s13075-022-02894-8
[2] Zhou, M., Theologis, A.A. and O’Connell, G.D. (2023) Understanding the Etiopathogenesis of Lumbar Intervertebral Disc Herniation: From Clinical Evidence to Basic Scientific Research. JOR Spine, 7, e1289.
https://doi.org/10.1002/jsp2.1289
[3] Hedman, T. and Rogers, A. (2025) Pathomechanics of Early-Stage Lumbar Intervertebral Disc Degradation Leading to Discogenic Pain—A Narrative Review. Bioengineering, 12, Article 389.
https://doi.org/10.3390/bioengineering12040389
[4] Lakshmeeha, T., Ajith Kumar, K.S., Vishanth, S.C., et al. (2019) Study of Correlation between Clinical Findings, Radiological and Intra Operative Findings in Lumbar Disc Prolapse. International Journal of Orthopaedics Sciences, 5, 65-68.
https://doi.org/10.22271/ortho.2019.v5.i3b.1509
[5] Pojskic, M., Bisson, E., Oertel, J., Takami, T., Zygourakis, C. and Costa, F. (2024) Lumbar Disc Herniation: Epidemiology, Clinical and Radiologic Diagnosis WFNS Spine Committee Recommendations. World Neurosurgery: X, 22, Article 100279.
https://doi.org/10.1016/j.wnsx.2024.100279
[6] 中华医学会骨科学分会脊柱外科学组, 中华医学会骨科学分会骨科康复学组. 腰椎间盘突出症诊疗指南[J]. 中华骨科杂志, 2020, 40(8): 477-487.
[7] Arifin, J., Gani, K.S. and Kennedy, D. (2025) Comparative Effectiveness of Microsurgery and Endoscopic Surgery in Lumbar Disc Herniation: A Systematic Review and Meta-Analysis. Narra Journal, 5, e1214.
https://doi.org/10.52225/narra.v5i1.1214
[8] Scrofani, R., Migliorini, F., Smajic, S., De Simone, M., Maffulli, N. and Iaconetta, G. (2025) Percutaneous Transforaminal Endoscopic Discectomy in Patients with Lumbar Disc Herniation: A Meta-Analysis. European Journal of Orthopaedic Surgery & Traumatology, 35, Article No. 276.
https://doi.org/10.1007/s00590-025-04374-6
[9] Musa, G., Abakirov, M.D., Arzoumi, N., Mamyrbaev, S.T., Castillo, R.E.B., Chmutin, G.E., et al. (2025) Is Transforaminal Endoscopic Discectomy the Best Option for Recurrent Lumbar Disc Herniation? A Systematic Review. International Journal of Spine Surgery, 19, Article 8698.
https://doi.org/10.14444/8698
[10] Krishnan, A., Aryal, A., Degulmadi, D., Mayi, S.C., Rai, R.R., Dave, M.B., et al. (2025) A New Classification System for Reporting Complications of Percutaneous Transforaminal Endoscopic Lumbar Decompression. Journal of Minimally Invasive Spine Surgery and Technique, 10, 3-21.
https://doi.org/10.21182/jmisst.2025.02019
[11] 王宁宁. 中西医结合康复护理对废用性膝关节挛缩患者下肢功能的影响研究[D]: [硕士学位论文]. 乌鲁木齐: 新疆医科大学, 2023.
[12] Guo, K., Wang, X., Lu, X., Yang, Y., Lu, W., Wang, S., et al. (2023) Effects of Sarcopenia and Frailty on Postoperative Recovery in Elderly Patients: A Prospective Cohort Study. Journal of Cachexia, Sarcopenia and Muscle, 14, 2642-2652.
https://doi.org/10.1002/jcsm.13337
[13] 张丽美, 潘力弢, 李一明. 电针促进周围神经损伤再生机制的研究进展[J]. 深圳中西医结合杂志, 2023, 33(20): 132-136.
[14] 董鑫, 陈馨雨. 《黄帝内经》“治痿独取阳明”理论探讨[J]. 江西中医药, 2025, 56(1): 18-20.
[15] 秦晓宽, 孙凯, 徐卫国, 高景华, 姜宏, 等. 腰椎间盘突出症中医循证实践指南[J]. 西部中医药, 2024, 37(5): 1-15.
[16] 王亚囡, 刘惠林, 孙宁, 等. 天轨悬吊训练对脑卒中偏瘫患者肌肉厚度、平衡和步行能力的影响[J]. 中国康复医学杂志, 2025, 40(8): 1189-1195.
[17] Lee, J.S., Lee, S.B., Kang, K.Y., et al. (2025) Review of Recent Treatment Strategies for Lumbar Disc Herniation (LDH) Focusing on Nonsurgical and Regenerative Therapies. Journal of Clinical Medicine, 14, Article 1196.
https://doi.org/10.3390/jcm14041196
[18] 沈兴利, 贺奇志, 周黎明, 等. 经皮椎间孔镜手术治疗腰椎间盘突出症的发展、麻醉与穿刺导航技术研究进展[J]. 颈腰痛杂志, 2024, 45(6): 1002-1006.
[19] 王一丹, 许阳阳, 苏宝科, 等. 经皮椎间孔镜技术治疗腰椎疾病的研究进展[J]. 中国临床解剖学杂志, 2020, 38(4): 488-491.
[20] Duman, F., Serarslan, Y., Ozturk, F., et al. (2020) Change in the Dimensions of the Lumbar Area Muscles after Surgery: MRI Analysis. Northern Clinics of Istanbul, 7, 478-486.
https://doi.org/10.14744/nci.2020.45144
[21] 刘震超, 王猛, 郭思晗, 等. 肌少症与废用性肌萎缩[J]. 中国骨质疏松杂志, 2024, 30(8): 1219-1223.
[22] 马天成, 王岩, 周丽芸, 孙亚迪, 李奕扬, 申佳慧, 李光, 等. 神经肌肉电刺激在骨骼肌废用性萎缩康复治疗中的研究进展[J]. 中国中西医结合外科杂志, 2024, 30(5): 757-762.
[23] 梁伟, 李文俊, 杨建华. 腰椎间盘突出症患者椎间孔镜术后复发的危险因素分析[J]. 中外医药研究, 2022, 1(6): 33-35.
[24] 李树文, 银和平, 吴一民, 白明, 杜志才, 武海军, 孟格栋. 显微内窥镜下髓核摘除治疗腰椎间盘突出症术中并发症原因分析及防治措施[J]. 中国骨伤, 2013, 26(3): 218-221.
[25] 郑杰, 郑德采, 凌珊珊, 等. 脑卒中偏瘫患者患侧下肢肌力与本体感觉的相关性及二者对膝过伸的影响[J]. 中国康复, 2025, 40(2): 98-101.
[26] 李东波. 基于“少阳主骨”理论电针经RhoA/ROCK信号通路调节膝关节本体感觉的机制研究[D]: [硕士学位论文]. 泸州: 西南医科大学, 2024.
[27] 陈泽华, 叶翔凌, 陈伟健, 等. 健康成年人下肢本体感觉与姿势稳定性的关系[J]. 中国组织工程研究, 2020, 24(29): 4692-4696.
[28] Xu, J., Zhou, X., Guo, X., Wang, G., Fu, S. and Zhang, L. (2018) Effects of Unilateral Electroacupuncture on Bilateral Proprioception in a Unilateral Anterior Cruciate Ligament Injury Model. Medical Science Monitor, 24, 5473-5479.
https://doi.org/10.12659/msm.909508
[29] 石涛利, 路志红, 熊利泽. 不同频率电针作用对中枢神经系统疾病诊治的效应机制研究[J]. 中华神经外科疾病研究杂志, 2017, 16(1): 92-94.
[30] 郑先波. 经皮椎间孔镜结合身痛逐瘀汤治疗腰椎间盘突出症30例临床观察[J]. 湖南中医杂志, 2017, 33(6): 85-86.
[31] 孙伊平, 张娇娇, 李婷, 吴海瑛, 尹晓娜. 夹脊穴研究进展概述[J]. 长春中医药大学学报, 2016, 32(5): 1092-1094.
[32] 邓利萍, 彭艳, 范小春. 温针灸治疗腰椎间盘突出症的疗效观察及对炎症因子的影响[J]. 上海针灸杂志, 2024, 43(4): 405-410.
[33] 何媛. 基于“阳明多气多血”理论运用温和灸足阳明经颈部穴位治疗急性脑梗死的临床疗效观察[D]: [硕士学位论文]. 成都: 成都中医药大学, 2023.
[34] 姬永宽, 白辰, 刘慧, 等. 阳明多气多血理论指导临床辨治的应用探析[J]. 环球中医药, 2024, 17(7): 1233-1238.
[35] 孙忠人, 胡其回, 郭峥, 等. 电项针临床应用进展[J]. 云南中医学院学报, 2021, 44(2): 98-102.
[36] 张邵青, 邱美榕, 吴追乐. “治痿独取阳明”的古今研究及临床应用[J]. 陕西中医药大学学报, 2016, 39(2): 9-12.
[37] 李容. 针灸治疗痿证的处方规律挖掘及临床观察研究[D]: [硕士学位论文]. 成都: 成都中医药大学, 2023.
[38] 鞠申丹, 宗蕾. 从“治痿独取阳明”谈痿证的针灸治疗[J]. 中国针灸, 2015, 35(9): 956-959.
[39] 孙忠人, 胡其回, 郭峥, 等. 基于《黄帝内经》“治痿独取阳明”探析脊髓损伤的治疗[J]. 长春中医药大学学报, 2022, 38(3): 249-252.
[40] 杨正军, 牛珲, 常虹, 等. 陕西省大骨节病患者关节活动度及肌肉萎缩相关调查[J]. 西安交通大学学报(医学版), 2024, 45(3): 470-477.
[41] 杨瑞, 曹凯, 赵伟, 等. 高强度间歇训练影响绝经后骨质疏松模型大鼠骨健康的机制[J]. 中国组织工程研究, 2024, 28(32): 5141-5147.
[42] Bao, J.F., She, Q.Y., Hu, P.P., et al. (2022) Irisin, a Fascinating Field in Our Times. Trends in Endocrinology & Metabolism, 33, 601-613.
https://doi.org/10.1016/j.tem.2022.06.003
[43] 刘美芹, 窦建新, 刘海霞. 鸢尾素与肌少症的相关性[J]. 生命的化学, 2023, 43(3): 395-401.
[44] Li, X., Zhu, X., Wu, H., Van Dyke, T.E., Xu, X., Morgan, E.F., et al. (2021) Roles and Mechanisms of Irisin in Attenuating Pathological Features of Osteoarthritis. Frontiers in Cell and Developmental Biology, 9, Article 703670.
https://doi.org/10.3389/fcell.2021.703670
[45] Mei, G., Wang, J., Wang, J., Ye, L., Yi, M., Chen, G., et al. (2024) The Specificities, Influencing Factors, and Medical Implications of Bone Circadian Rhythms. The FASEB Journal, 38, e23758.
https://doi.org/10.1096/fj.202302582rr
[46] 吕俊刚, 翟莉, 王娜, 等. 中老年健康体检男性血清骨钙素水平的临床关联因素[J]. 武警医学, 2025, 36(4): 295-300.
[47] Wang, J.S., Mazur, C.M. and Wein, M.N. (2021) Sclerostin and Osteocalcin: Candidate Bone-Produced Hormones. Frontiers in Endocrinology, 12, Article 584147.
https://doi.org/10.3389/fendo.2021.584147
[48] Liu, S., Gao, F., Wen, L., Ouyang, M., Wang, Y., Wang, Q., et al. (2017) Osteocalcin Induces Proliferation via Positive Activation of the PI3K/Akt, P38 MAPK Pathways and Promotes Differentiation through Activation of the GPRC6A-ERK1/2 Pathway in C2C12 Myoblast Cells. Cellular Physiology and Biochemistry, 43, 1100-1112.
https://doi.org/10.1159/000481752
[49] Si, B., Zhu, H., Wei, X., Li, S. and Wu, X. (2024) The Mechanism of Static Postural Control in the Impact of Lower Limb Muscle Strength Asymmetry on Gait Performance in the Elderly. Peer Journal, 12, e17626.
https://doi.org/10.7717/peerj.17626
[50] 黄萍, 齐进, 邓廉夫, 等. 正常青年人自然步态下肢肌的表面肌电图分析[J]. 中国组织工程研究, 2012, 16(20): 3680-3684.
[51] 叶玉琴, 金海莲, 朱丹, 等. 针极肌电图及表面肌电图在神经肌肉疾病中的应用[J]. 中风与神经疾病杂志, 2013, 30(6): 571-572.
[52] 李芳, 安丙辰, 郑洁皎. 表面肌电图在脑卒中患者手神经肌肉功能评定中的应用[J]. 中国康复理论与实践, 2015, 31(3): 280-283.
[53] Zhu, S., Lin, W., Chen, S., et al. (2019) The Correlation of Muscle Thickness and Pennation Angle Assessed by Ultrasound with Sarcopenia in Elderly Chinese Community Dwellers. Clinical Interventions in Aging, 14, 987-996.
https://doi.org/10.2147/cia.s201777