少腹逐瘀汤加减治疗寒凝血瘀型原发性痛经的研究进展

Research Progress on Modified Shaofu Zhuyu Decoction in Treating Primary Dysmenorrhea of Cold-Coagulation and Blood-Stasis Syndrome

摘要: 原发性痛经(Primary Dysmenorrhea, PD)为妇科临床的常见病、多发病，寒凝血瘀证为临床最常见证型。少腹逐瘀汤出自《医林改错》，为治疗寒凝血瘀型原发性痛经代表方，具有温经散寒、活血逐瘀止痛功效。临床常用该方进行加减化裁，或联合艾灸、浮针、中药穴位贴敷等中医辅助疗法，提高临床疗效。本文对近年少腹逐瘀汤加减治疗寒凝血瘀型原发性痛经的相关研究进展予以综述，从发病机制、方义解析、现代药理机制、临床运用、现存问题与展望几个方面进行综述，为该病的中医药临床辨证用药提供参考。

Abstract: Primary Dysmenorrhea (PD) is a common and frequently occurring gynecological disease, and cold-coagulation and blood-stasis syndrome is its most frequent clinical pattern. Originating from Yi Lin Gai Cuo (Correction of Errors in Medical Works), Shaofu Zhuyu Decoction is a classic prescription for PD characterized by cold-coagulation and blood-stasis syndrome. It has the functions of warming meridians to dispel cold, activating blood circulation to remove stasis and alleviating pain. Clinically, its modified version is widely used, or combined with adjuvant TCM therapies including moxibustion, floating-needle therapy and herbal acupoint application to improve therapeutic effects. This article reviews recent studies on modified Shaofu Zhuyu Decoction in the treatment of PD with cold-coagulation and blood-stasis syndrome. It summarizes the understanding of etiology-pathogenesis, analysis of the formula’s rationale, modern pharmacological mechanisms, clinical application, existing problems and prospects, so as to provide references for TCM syndrome-differentiated medication for this disease.