β-环糊精/羟基磷灰石的制备与性能研究

Study on Preparation and Characterization of β-Cyclodextrin/Hydroxyapatite

摘要: 本研究分别以CaCl₂和H₃PO₄为钙源和磷源，NaOH为pH调节剂，成功制备了β-环糊精(β-CD)/羟基磷灰石(HAP)复合物。借助傅里叶变换红外光谱(FT-IR)、热重分析(TG)和扫描电镜(SEM)对反应产物进行了表征，研究β-CD浓度对产物的组成、热稳定性、形貌等的影响。结果表明，β-CD可以影响产物组成和形貌，随着β-CD浓度的增大，产物由最初的无规团聚逐渐变成针状、棒状结构。结合β-CD的分子结构及其自组装性能，对β-CD与HAP的反应机理进行了初步探讨。

Abstract: β-cyclodextrin/hydroxyapatite was prepared by using calcium chloride (CaCl₂) and phosphate (H₃PO₄) as the resource of calcium and phosphorus, respectively. During the synthesis, NaOH was used as pH adjusting agent to control the pH of the solution. Fourier transform infrared spectros-cope (FT-IR), thermogravimetric analysis (TG) and scanning electron microscopy (SEM) were used to characterize the product. The effects of the concentration of β-cyclodextrin on the size, compo-sition and morphology of the product were investigated. The results showed that β-cyclodextrin could significantly influence the composition and morphology of the product. With the increasing of β-cyclodextrin concentration, the structure of the product grew from the initial random aggregation to needle-like and rodlike structures. The reaction mechanism between β-CD and HAP was discussed on the basis of the special molecular structure of β-CD and its self-assemble property.