液体T2弛豫时间测量CPMG磁共振脉冲序列实现与应用
The Implementation and Application of CPMG NMR Pulse Sequence for Measuring T2 Relaxation Time with Clinical MRI Scanner
DOI: 10.12677/HJBM.2017.74012, PDF,    科研立项经费支持
作者: 赵子剑, 王进喜*, 单常征, 潘 洋, 刘 锦：泰山医学院放射学院，山东 泰安；聂 斌：泰山医学院医学信息工程学院，山东 泰安
关键词: 核磁共振；脉冲序列；CPMG；实现应用；Nuclear Magnetic Resonance； Pulse Sequence； CPMG； Implementation and Application
摘要: 目的：探讨在i_Open 0.36T医用磁共振成像(MRI)系统上开发测试液体T2横向弛豫时间Carr-Purcell-Meiboom-Gill (CPMG)序列的可行性与实现方法。方法：pascal语言编辑源程序，可调参数控制激发脉冲波形，相位，幅度，持续时间等属性，回波间隔，数据采集次数，采样点数，采样时间等，编排数据记录方式，满足反演求T2的需要。编译源程序，上机调试实验，测试样品T2，与标准值比较。结果：完成了CPMG序列源代码，编译的可行性文件能够在商业磁共振成像仪上运行，测得的CuSO4溶液样品的T2值为197.479 ms。结论：利用该方法实现的CPMG序列所测样品T2值与标称值一致，满足实际应用需要，利用该方法实现CPMG序列是可行的。
Abstract: Objective: To implement Carr-Purcell-Meiboom-Gill pulse sequence for T2 relaxation measuring in i_Open 0.36T clinical MRI scanner. Methods: Pascal language is engaged to edit source code. Waveform, phase, amplitude and maintaining time of the excited RF pulse, spacing time of echoes, number of times of data sampling, sampling points, sampling time, and so on are all controlled by sequence parameters. Data logging form was arranged to meet the need of T2 inversion. Source code of sequence was compiled to executable file and is loaded to RINMR software. Comparison was taken between measuring time of sample of CuSO4 solution with our pulse sequence and the given standard value. Results: Source code of CPMG sequence was done as well as the exe file can run with commercial MRI instrumentation. The measuring T2 relaxation time of sample was 197.479 ms. Conclusion: The T2 value computed with our data acquired by our CPMG sequence is consistent with the given nominal value. The CPMG sequence adequately satisfies the practical application and the method can be used to implement the pulse sequence.
文章引用：赵子剑, 王进喜, 聂斌, 单常征, 潘洋, 刘锦. 液体T2弛豫时间测量CPMG磁共振脉冲序列实现与应用[J]. 生物医学, 2017, 7(4): 73-78. https://doi.org/10.12677/HJBM.2017.74012

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