长链非编码RNA在神经系统疾病中的研究进展
Advance in Research on Long Noncoding RNA of Central Nervous System Diseases
摘要: 长链非编码RNA是长度超过200个核苷酸的非编码RNA分子，在神经系统发育、神经元分化、突触可塑性等生物过程中发挥重要作用，参与了多种神经系统疾病的发生发展过程。本文主要阐述lncRNA在神经系统疾病包括缺血性脑卒中、帕金森氏病、多发性硬化中的研究进展。
Abstract: Long noncoding RNAs (lncRNAs) represent a class of transcripts longer than 200 nucleotides but do not encode proteins. Emerging evidence shows that lncRNAs play critical roles in many biological processes, such as brain development, neural differentiation, and synaptic plasticity, and par-ticipate in the pathogenesis of a variety of central nervous system (CNS) diseases. This paper is to review the research progress of lncRNA in CNS diseases include ischemic stroke, Parkinson’s dis-ease, and multiple sclerosis.
文章引用：李舒, 毕薪燃. 长链非编码RNA在神经系统疾病中的研究进展[J]. 临床医学进展, 2017, 7(5): 290-294. https://doi.org/10.12677/ACM.2017.75048

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