糖尿病视网膜病变合并视网膜静脉阻塞危险因素的病例对照研究

A Case-Control Observation on Risk Factors in Diabetic Retinopathy Combined with Retinal Vein Occlusion

摘要: 目的：探讨糖尿病视网膜病变合并视网膜静脉阻塞的患者与全身性疾病、眼部疾病以及相关危险因素的关系。方法：采用1:3配比设计的病例对照研究方法。将2013年1月至2016年3月深圳市第二人民医院收治的30例糖尿病视网膜病变合并视网膜静脉阻塞的患者作为研究组；对照组：选择与研究组年龄、性别以及糖尿病视网膜病变分级相匹配的90例糖尿病视网膜病变的患者。两组之间分别进行全身性和眼局部性疾病以及相关危险因素的统计学比较。结果：观察组高血压、高脂血症和颈动脉血栓的患病率明显高于对照组(P < 0.05)，而冠心病、吸烟和饮酒习性上差异无统计学意义(P > 0.05)。结论：高血压、高脂血症以及颈动脉血栓为糖尿病并发视网膜静脉阻塞的高危因素，及时诊断和治疗高血压、高脂血症，控制颈动脉血栓对于视网膜静脉的防治具有指导意义。

Abstract: Objective: To investigate the relationship among diabetic retinopathy combined with retinal vein occlusion and major systemic diseases, ocular diseases and related risk factors. Methods: We per-formed a retrospective case-control study from November 2013 to March 2016. 30 patients with diabetic retinopathy combined with retinal vein occlusion were in observational group. Other 90 diabetic retinopathy patients without retinal vein occlusion were in control group who were matched with the ones in observational group to a one-to-three partnership according to the age, gender and diabetic retinopathy degree. The systematic diseases, ocular local diseases and the re-lated risk factors were statistically analyzed and compared. Results: The incidence of hypertension, hyperlipemia and carotid arterial thrombosis in observational group were significantly higher than that in the control group (P < 0.05). There was no significant difference of cardiovascular diseases, and smoking and drinking between the two groups (>0.05). Conclusion: Hypertension hyperlipidemia and carotid arterial thrombosis are factors in diabetes population with occurrence of retinal vein occlusion.