|
[1]
|
Raghu, G., Collard, H.R., Egan, J.J., et al. (2011) An Official ATS/ERS/JRS/ALAT Statement: Idiopathic Pulmonary Fibrosis: Evidence-Based Guidelines for Diagnosis and Management. American Journal of Respiratory and Critical Care Medicine, 183, 788-824.
[Google Scholar] [CrossRef]
|
|
[2]
|
Todd, N.W., Luzina, I.G. and Atamas, S.P. (2012) Molecular and Cellular Mechanisms of Pulmonary Fibrosis. Fibrogenesis & Tissue Repair, 5, 11.
[Google Scholar] [CrossRef] [PubMed]
|
|
[3]
|
Crystal, R.G., Fulmer, J.D., Roberts, W.C., et al. (1976) Idiopathic Pulmonary Fibrosis. Clinical, Histologic, Radiographic, Physiologic, Scintigraphic, Cytologic, and Biochemical Aspects. Annals of Internal Medicine, 85, 769-788.
[Google Scholar] [CrossRef] [PubMed]
|
|
[4]
|
Hamman, L. and Rich, A.R. (1935) Fulminating Diffuse Inter-stitial Fibrosis of the Lungs. Transactions of the American Clinical and Climatological Association, 51, 154-163.
|
|
[5]
|
Scadding, J.G. and Hinson, K.F. (1967) Diffuse Fibrosing Alveolitis (Diffuse Interstitial Fibrosis of the Lungs). Correlation of Histology at Biopsy with Prognosis. Thorax, 22, 291-304.
[Google Scholar] [CrossRef] [PubMed]
|
|
[6]
|
Selman, M., King, T.E. and Pardo, A. (2001) Idiopathic Pulmonary Fi-brosis: Prevailing and Evolving Hypotheses about Its Pathogenesis and Implications for Therapy. Annals of Internal Medicine, 134, 136-151.
[Google Scholar] [CrossRef] [PubMed]
|
|
[7]
|
Barnes, P.J. and Adcock, I.M. (2009) Gluco-corticoid Resistance in Inflammatory Diseases. Lancet, 373, 1905-1917.
[Google Scholar] [CrossRef]
|
|
[8]
|
Homer, R.J., Elias, J.A., Lee, C.G., et al. (2011) Modern Concepts on the Role of Inflammation in Pulmonary Fibrosis. Archives of Pathology & Laboratory Medicine, 135, 780-788.
|
|
[9]
|
Wynn, T.A. (2011) Integrating Mechanisms of Pulmonary Fibrosis. Journal of Experimental Medicine, 208, 1339-1350.
[Google Scholar] [CrossRef] [PubMed]
|
|
[10]
|
Fredberg, U. and Stengaard-Pedersen, K. (2008) Chronic Tendinopathy Tissue Pathology, Pain Mechanisms, and Etiology with a Special Focus on Inflammation. Scan-dinavian Journal of Medicine & Science in Sports, 18, 3-15.
[Google Scholar] [CrossRef] [PubMed]
|
|
[11]
|
Schulze-Tanzil, G., Al-Sadi, O., Wiegand, E., et al. (2011) The Role of Pro-Inflammatory and Immunoregulatory Cytokines in Tendon Healing and Rupture: New Insights. Scandinavian Journal of Medicine & Science in Sports, 21, 337-351.
[Google Scholar] [CrossRef] [PubMed]
|
|
[12]
|
Zhang, H.Y. and Phan, S.H. (1999) Inhibition of Myofi-broblast Apoptosis by Transforming Growth Factor β1. American Journal of Respiratory Cell and Molecular Biology, 21, 658-665.
[Google Scholar] [CrossRef] [PubMed]
|
|
[13]
|
Loppow, D., Schleiss, M.B., Kanniess, F., et al. (2001) In Patients with Chronic Bronchitis a Four Week Trial with Inhaled Steroids Does Not Attenuate Airway Inflammation. Respiratory Medicine, 95, 115-121.
[Google Scholar] [CrossRef] [PubMed]
|
|
[14]
|
Leung, D.Y., Martin, R.J., Szefler, S.J., et al. (1995) Dysregulation of Interleukin 4, Interleukin 5, and Interferon Gamma Gene Expression in Steroid-Resistant Asthma. Journal of Ex-perimental Medicine, 181, 33-40.
[Google Scholar] [CrossRef] [PubMed]
|
|
[15]
|
Kay, A.B., Diaz, P., Carmicheal, J., et al. (1981) Corticoster-oid-Resistant Chronic Asthma and Monocyte Complement Receptors. Clinical & Experimental Immunology, 44, 576-580.
|
|
[16]
|
Corrigan, C.J., Brown, P.H., Barnes, N.C., et al. (1991) Glucocorticoid Resistance in Chronic Asthma. Peripheral Blood T Lymphocyte Activation and Comparison of the T Lymphocyte Inhibitory Effects of Glucocorticoids and Cyclosporin A. The American Review of Respiratory Disease, 144, 1026-1032.
[Google Scholar] [CrossRef] [PubMed]
|
|
[17]
|
Yang, M., Kumar, R.K., Hansbro, P.M., et al. (2012) Emerging Roles of Pulmonary Macrophages in Driving the Development of Severe Asthma. Journal of Leukocyte Biology, 91, 557-569.
[Google Scholar] [CrossRef] [PubMed]
|
|
[18]
|
Sliwinska-Stanczyk, P., Pazdur, J., Ziolkowska, M., et al. (2007) The Effect of Methylprednisolone on Proliferation of PBMCs Obtained from Steroid-Sensitive and Ster-oid-Resistant Rheumatoid Arthritis Patients. Scandinavian Journal of Rheumatology, 36, 167-171.
[Google Scholar] [CrossRef] [PubMed]
|
|
[19]
|
Farrell, R.J. and Kelleher, D. (2003) Glucocorticoid Resistance in Inflammatory Bowel Disease. Journal of Endocrinology, 178, 339-346.
[Google Scholar] [CrossRef] [PubMed]
|
|
[20]
|
Hearing, S.D., Norman, M., Probert, C.S., et al. (1999) Predicting Therapeutic Outcome in Severe Ulcerative Colitis by Measuring in Vitro Steroid Sensitivity of Proliferating Peripheral Blood Lymphocytes. Gut, 45, 382-388.
[Google Scholar] [CrossRef] [PubMed]
|
|
[21]
|
Markart, P., Luboeinski, T., Korfei, M., et al. (2009) Alveolar Oxidative Stress Is Associated with Elevated Levels of Nonenzymatic Low-Molecular-Weight Antioxidants in Patients with Different Forms of Chronic Fibrosing Interstitial Lung Diseases. Antioxidants & Redox Signaling, 11, 227-240.
[Google Scholar] [CrossRef] [PubMed]
|
|
[22]
|
De Nardo, D., De Nardo, C.M. and Latz, E. (2014) New Insights into Mechanisms Controlling the NLRP3 Inflammasome and Its Role in Lung Disease. American Journal of Pathology, 184, 42-54.
[Google Scholar] [CrossRef] [PubMed]
|
|
[23]
|
Zuo, F.R., Kaminski, N., Eugui, E., et al. (2002) Gene Expres-sion Analysis Reveals Matrilysin as a Key Regulator of Pulmonary Fibrosis in Mice and Humans. Proceedings of the National Academy of Sciences of the United States of America, 99, 6292-6297.
[Google Scholar] [CrossRef] [PubMed]
|
|
[24]
|
Wynn, T.A. (2007) Common and Unique Mechanisms Regulate Fibrosis in Various Fibroproliferative Diseases. Journal of Clinical Investigation, 117, 524-529.
[Google Scholar] [CrossRef]
|
|
[25]
|
Hinz, B., Phan, S.H., Thannickal, V.J., et al. (2007) The Myofibroblast: One Function, Multiple Origins. American Journal of Pathology, 170, 1807-1816.
[Google Scholar] [CrossRef] [PubMed]
|
|
[26]
|
Yin, Q., Wang, W., Cui, G., et al. (2018) Potential Role of the Jagged1/Notch1 Signaling Pathway in the Endothelial-Myofibroblast Transition during BLM-Induced Pulmonary Fi-brosis. Journal of Cellular Physiology, 233, 2451-2463.
[Google Scholar] [CrossRef] [PubMed]
|
|
[27]
|
Bolanos, A.L., Milla, C.M., Lira, J.C., et al. (2012) Role of Sonic Hedgehog in Idiopathic Pulmonary Fibrosis. American Journal of Physiology-Lung Cellular and Molecular Physiology, 303, L978-L990.
[Google Scholar] [CrossRef] [PubMed]
|
|
[28]
|
Ho, Y.Y., Lagares, D., Tager, A.M., et al. (2014) Fibrosis—A Lethal Component of Systemic Sclerosis. Nature Reviews Rheumatology, 10, 390-402.
[Google Scholar] [CrossRef] [PubMed]
|
|
[29]
|
Hinz, B., Phan, S.H., Thannickal, V.J., et al. (2012) Recent De-velopments in Myofibroblast Biology: Paradigms for Connective Tissue Remodeling. American Journal of Pathology, 180, 1340-1355.
[Google Scholar] [CrossRef] [PubMed]
|
|
[30]
|
Van Meeteren, L.A. and Ten Dijke, P. (2012) Regulation of Endothelial Cell Plasticity by TGF-Beta. Cell and Tissue Research, 347, 177-186.
[Google Scholar] [CrossRef] [PubMed]
|
|
[31]
|
Hashimoto, N., Phan, S.H., Imaizumi, K., et al. (2010) Endo-thelial-Mesenchymal Transition in Bleomycin-Induced Pulmonary Fibrosis. American Journal of Respiratory Cell and Molecular Biology, 43, 161-172.
[Google Scholar] [CrossRef]
|
|
[32]
|
Guan, R., Wang, X., Zhao, X., et al. (2016) Emodin Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Rats by Suppressing Epithelial-Mesenchymal Transition and Fibroblast Activation. Scientific Reports, 6, Article No. 35696.
[Google Scholar] [CrossRef] [PubMed]
|
|
[33]
|
Aono, Y., Kishi, M., Yokota, Y., et al. (2014) Role of Platelet-Derived Growth Factor/Platelet-Derived Growth Factor Receptor Axis in the Trafficking of Circulating Fibrocytes in Pulmonary Fibrosis. American Journal of Respiratory Cell and Molecular Biology, 51, 793-801.
[Google Scholar] [CrossRef]
|
|
[34]
|
Gordon, S. and Martinez, F.O. (2010) Alternative Activation of Macrophages: Mechanism and Functions. Immunity, 32, 593-604.
[Google Scholar] [CrossRef] [PubMed]
|
|
[35]
|
Waisberg, D.R., Parra, E.R., Barbas-Filho, J.V., et al. (2012) Increased Fibroblast Telomerase Expression Precedes Myofibroblast Alpha-Smooth Muscle Actin Expression in Idio-pathic Pulmonary Fibrosis. Clinics (Sao Paulo), 67, 1039-1046.
[Google Scholar] [CrossRef] [PubMed]
|
|
[36]
|
Wynes, M.W., Edelman, B.L., Kostyk, A.G., et al. (2011) In-creased Cell Surface Fas Expression Is Necessary and Sufficient to Sensitize Lung Fibroblasts to Fas Ligation-Induced Apoptosis: Implications for Fibroblast Accumulation in Idiopathic Pulmonary Fibrosis. Journal of Immunology, 187, 527-537.
[Google Scholar] [CrossRef] [PubMed]
|
|
[37]
|
Frankel, S.K., Cosgrove, G.P., Cha, S.I., et al. (2006) TNF-Alpha Sensitizes Normal and Fibrotic Human Lung Fibroblasts to Fas-Induced Apoptosis. American Journal of Respiratory Cell and Molecular Biology, 34, 293-304.
[Google Scholar] [CrossRef]
|
|
[38]
|
Goldberg, M.T., Han, Y.P., Yan, C., et al. (2007) TNF-Alpha Suppresses Alpha-Smooth Muscle Actin Expression in Human Dermal Fibroblasts: An Implication for Abnormal Wound Healing. Journal of Investigative Dermatology, 127, 2645-2655.
[Google Scholar] [CrossRef] [PubMed]
|
|
[39]
|
Zhang, H.S. and Wang, S.Q. (2006) Salvianolic Acid B from Salvia miltiorrhiza Inhibits Tumor Necrosis Factor-Alpha (TNF-Alpha)-Induced MMP-2 Upregulation in Human Aortic Smooth Muscle Cells via Suppression of NAD(P)H Oxidase-Derived Reactive Oxygen Species. Journal of Molecular and Cellular Cardiology, 41, 138-148.
[Google Scholar] [CrossRef] [PubMed]
|
|
[40]
|
Redente, E.F., Keith, R.C., Janssen, W., et al. (2014) Tumor Necrosis Factor-Alpha Accelerates the Resolution of Established Pulmonary Fibrosis in Mice by Targeting Profibrotic Lung Macrophages. American Journal of Respiratory Cell and Molecular Biology, 50, 825-837.
[Google Scholar] [CrossRef]
|
|
[41]
|
Le, T.T., Karmouty-Quintana, H., Melicoff, E., et al. (2014) Blockade of IL-6 Trans Signaling Attenuates Pulmonary Fibrosis. The Journal of Immunology, 193, 3755-3768.
[Google Scholar] [CrossRef] [PubMed]
|
|
[42]
|
Borcherding, F., Nitschke, M., Hundorfean, G., et al. (2010) The CD40-CD40L Pathway Contributes to the Proinflammatory Function of Intestinal Epithelial Cells in Inflammatory Bowel Disease. American Journal of Pathology, 176, 1816-1827.
[Google Scholar] [CrossRef] [PubMed]
|
|
[43]
|
Santilli, F., Basili, S., Ferroni, P., et al. (2007) CD40/CD40L System and Vascular Disease. Internal and Emergency Medicine, 2, 256-268.
[Google Scholar] [CrossRef] [PubMed]
|
|
[44]
|
Gillespie, E.F., Raychaudhuri, N., Papageorgiou, K.I., et al. (2012) Interleukin-6 Production in CD40-Engaged Fibrocytes in Thyroid-Associated Ophthalmopathy: Involvement of Akt and NF-kappaB. Investigative Ophthalmology & Visual Science, 53, 7746-7753.
[Google Scholar] [CrossRef] [PubMed]
|
|
[45]
|
Douglas, R.S., Mester, T., Ginter, A., et al. (2014) Thyrotropin Re-ceptor and CD40 Mediate Interleukin-8 Expression in Fibrocytes: Implications for Thyroid-Associated Ophthalmopathy (An American Ophthalmological Society thesis). Transactions of the American Ophthalmological Society, 112, 26-37.
|
|
[46]
|
Faner, R., Rojas, M., Macnee, W., et al. (2012) Abnormal Lung Aging in Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine, 186, 306-313.
[Google Scholar] [CrossRef]
|
|
[47]
|
Kinnula, V.L. and Crapo, J.D. (2003) Superoxide Dismutases in the Lung and Human Lung Diseases. American Journal of Respiratory and Critical Care Medicine, 167, 1600-1619.
[Google Scholar] [CrossRef]
|
|
[48]
|
Jones, D.P. (2006) Extracellular Redox State: Refining the Definition of Oxidative Stress in Aging. Rejuvenation Research, 9, 169-181.
[Google Scholar] [CrossRef] [PubMed]
|
|
[49]
|
Winterbourn, C.C. (2008) Reconciling the Chemistry and Biology of Reactive Oxygen Species. Nature Chemical Biology, 4, 278-286.
[Google Scholar] [CrossRef] [PubMed]
|
|
[50]
|
胡玉洁, 董文杰. 氧化应激促进肺间质纤维化的机制[J]. 国际呼吸杂志, 2012, 8(32): 605-607.
|
|
[51]
|
杨丽, 吕晓东, 刘勇明, 等. 中医药防治肺纤维化氧化应激作用机制研究进展[J]. 世界中西医结合杂志, 2017, 12(3): 297-300.
|
|
[52]
|
Kliment, C.R. and Oury, T.D. (2010) Oxidative Stress, Extracellular Matrix Targets, and Idiopathic Pulmonary Fibrosis. Free Radical Biology & Medicine, 49, 707-717.
[Google Scholar] [CrossRef] [PubMed]
|
|
[53]
|
Kamp, D.W., Graceffa, P., Pryor, W.A., et al. (1992) The Role of Free Radicals in Asbestos-Induced Diseases. Free Radical Biology & Medicine, 12, 293-315.
[Google Scholar] [CrossRef]
|
|
[54]
|
Juul, K., Tybjaerg-Hansen, A., Mortensen, J., et al. (2005) Factor V Leiden Homozygosity, Dyspnea, and Reduced Pulmonary Function. Archives of Internal Medicine, 165, 2032-2036.
[Google Scholar] [CrossRef] [PubMed]
|
|
[55]
|
Sode, B.F., Dahl, M., Nielsen, S.F., et al. (2010) Venous Thromboembolism and Risk of Idiopathic Interstitial Pneumonia: A Nationwide Study. American Journal of Respiratory and Critical Care Medicine, 181, 1085-1092.
[Google Scholar] [CrossRef]
|
|
[56]
|
Kotani, I., Sato, A., Hayakawa, H., et al. (1995) Increased Procoagulant and Antifibrinolytic Activities in the Lungs with Idiopathic Pulmonary Fibrosis. Thrombosis Research, 77, 493-504.
[Google Scholar] [CrossRef] [PubMed]
|
|
[57]
|
Imokawa, S., Sato, A., Hayakawa, H., et al. (1997) Tissue Factor Expression and Fibrin Deposition in the Lungs of Patients with Idiopathic Pulmonary Fibrosis and Systemic Sclerosis. American Journal of Respiratory and Critical Care Medicine, 156, 631-636.
[Google Scholar] [CrossRef] [PubMed]
|
|
[58]
|
Wygrecka, M., Kwapiszewska, G., Jablonska, E., et al. (2011) Role of Protease-Activated Receptor-2 in Idiopathic Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine, 183, 1703-1714.
[Google Scholar] [CrossRef]
|