人工晶体计算公式在正常眼轴合并浅前房白内障患者中的准确性比较

Accuracy of Various Intraocular Lens Calculation Formulas in Shallow Anterior Chamber Patients with Normal Axial Length

摘要: 目的：比较5种人工晶体(Intraocular lens, IOL)计算公式(Haigis、SRK II、HofferQ、Holladay1以及 SRK/T)在预测正常眼轴合并浅前房白内障患者术后屈光度的准确性，探讨适合此类患者的IOL计算公式。方法：回顾性系列病例研究。纳入2016年1月至2017年10月于青岛大学附属医院眼科就诊的正常眼轴长度(Axial length, AL)合并浅前房白内障患者共45例(45眼)。使用IOL Master计算不同公式的预测术后屈光度数，术后3至8周验光确定患者实际术后屈光度数，计算屈光误差、绝对屈光误差。应用 SPSS19.0进行统计学分析，比较对不同IOL计算公式的屈光误差、绝对屈光误差及屈光误差分布。结果：Haigis公式的平均屈光误差(−0.13 ± 0.76 D)最小，与Hoffer Q (−0.34 ± 0.74 D，P < 0.01)、Holladay1 (−0.33 ± 0.73 D, P < 0.01)以及SRK/T(−0.31 ± 0.72 D，P < 0.01)公式比较，差异具有统计学意义。Haigis、SRK II、HofferQ、Holladayl以及SRK/T公式的平均绝对屈光误差分别为0.58 ± 0.50 D, 0.62 ± 0.50 D, 0.62 ± 0.51 D，0.61 ± 0.51 D及0.58 ± 0.53 D，差异无统计学意义(χ² = 4.027, P = 0.402)。不同IOL计算公式的屈光误差分布差异无统计学意义(χ² = 3.782, P = 0.872)。结论：Haigis公式在正常眼轴合并浅前房白内障患者术后屈光度预测中的准确性高，选择Haigis公式在将有助于减少屈光误差。

Abstract: Objective: To compare the accuracy of five intraocular lens calculation formulas (Haigis, SRK II, Hoffer Q, Holladay1 and SRK/T) in shallow anterior chamber patients with normal axial length. Methods: 45 patients who underwent uncomplicated cataract surgery were involved in this ret-rospective analysis. This study was performed in the Department of Ophthalmology at the Affiliated Hospital of Qingdao University from January 2016 to October 2017. The IOL Master was used to predict the refractive outcomes for five formulas. Actual postoperative refractions were taken on 3 to 8 weeks after surgery. Refractive error and absolute refractive error were calculated. The SPSS19.0 was used for statistical analysis to compare the refractive errors, absolute refractive er-rors and the refractive error distribution of different IOL formulas. Results: The mean refractive error of the Haigis formula (–0.13 ± 0.76 D) differed significantly from Hoffer Q (–0.34 ± 0.74 D, P < 0.01), Holladay1 (–0.33 ± 0.73 D, P < 0.01) and SRK/T (–0.31 ± 0.72 D, P < 0.01) formulas. The mean absolute refractive error were 0.58 ± 0.50 D，0.62 ± 0.50 D, 0.62 ± 0.51 D, 0.61 ± 0.51 D and 0.58 ± 0.53 D with Haigis, SRK II, HofferQ, Holladay1, and SRK/T formulas, respectively, and there was no significant differences among them (χ² = 4.027, P = 0.402). There was no significant difference in the distribution of refractive error between different IOL formulas (χ² = 3.782, P = 0.872). Conclusion: The Haigis formula can predict refraction in shallow anterior chamber patients with normal axial length with less error.