房颤射频消融术术后复发相关因素研究进展
Progress in Research on Factors of Atrial Fibrillation Recurrence after Radiofrequency Ablation
DOI: 10.12677/ACM.2018.82037, PDF,   
作者: 杨美玲, 赵 青, 蔡尚郎, 于艳飞：青岛大学医学院附属医院心血管内科，山东 青岛
关键词: 综述；心房颤动；射频消融术；复发；Review； Atrial Fibrillation； Radiofrequency Ablation； Recurrence
摘要: 心房颤动(atrial fibrillation，房颤)是临床工作中最常见的心律失常之一，可引起血流动力学改变导致血栓事件发生，是房颤患者预后不良的重要原因。目前房颤的治疗主要为药物治疗和非药物治疗，药物治疗以控制心室率为主，非药物治疗有电转复、射频消融术。射频消融术是对药物治疗反应性差的病人恢复窦性心律的重要方法，被广泛应用于临床。手术常见并发症为射频消融术术后复发，研究房颤患者射频消融术术后复发的相关因素，识别复发的高危患者，有助于指导临床治疗。本研究就房颤患者射频消融术术后复发的相关因素进行概述。
Abstract: Atrial fibrillation (AF) is one of the most common arrhythmias in clinical work. It can cause he-modynamic change and lead to thrombotic events. It is an important cause of bad prognosis in pa-tients with atrial fibrillation. At present, the treatment of atrial fibrillation is drug treatment and non-drug treatment. Drug treatment mainly controls the ventricular rate, and non-drug treatment includes electrical conversion, radiofrequency ablation. Radiofrequency ablation is an important method for restoring sinus rhythm in patients with poor response to drug therapy. Radiofrequency ablation is widely used in clinical practice. The common complication of radiofrequency ablation is recurrence. Studying the relevant factors and identifying patients with high rate of recurrence will help to guide clinical treatment. This study outlines factors of atrial fibrillation recurrence after radiofrequency ablation.
文章引用：杨美玲, 赵青, 蔡尚郎, 于艳飞. 房颤射频消融术术后复发相关因素研究进展[J]. 临床医学进展, 2018, 8(2): 217-221. https://doi.org/10.12677/ACM.2018.82037

参考文献

[1] Arbelo, E., Brugada, J., Hindricks, G., et al. (2014) The Atrial Fibrillation Ablation Pilot Study: A European Survey on Methodology and Results of Catheter Ablation for Atrial Fibrillation Conducted by the European Heart Rhythm Asso-ciation. European Heart Journal, 35, 1466-1478.
[Google Scholar] [CrossRef] [PubMed]
[2] 陶惠伟, 刘少稳, 林佳雄, 等. P波离散度与阵发性房颤经导管射频消融术后复发的关系[J]. 中国临床医学, 2009, 16(4): 498-500.
[3] 武冰琳, 汪祥海. 炎症因子与心房颤动消融术后复发的关系[J]. 临床荟萃, 2016, 31(9): 1038-1041.
[4] 郑桂安, 林春艺, 翁兰, 等. 左心耳体积对心房颤动导管射频消融术后复发的预测价值[J]. 中华心血管病杂志, 2017, 45(11): 924-929.
[5] Di, B.L., Burkhardt, J.D., Mohanty, P., et al. (2016) Left Atrial Ap-pendage Isolation in Patients with Longstanding Persistent AF Undergoing Catheter Ablation: BELIEF Trial. Journal of the American College of Cardiology, 68, 1929-1940.
[Google Scholar] [CrossRef] [PubMed]
[6] Acet, H., Ertaş, F., Akıl, M.A., et al. (2014) New Inflammatory Predictors for Non-Valvular Atrial Fibrillation: Echocardiographic Epicardial Fat Thickness and Neutrophil to Lymphocyte Ratio. International Journal of Cardiovascular Imaging, 30, 81-89.
[Google Scholar] [CrossRef] [PubMed]
[7] Sonmez, O., Ertem, F.U., Vatankulu, M.A., et al. (2014) Novel Fibro-Inflammation Markers in Assessing Left Atrial Remodeling in Non-Valvular Atrial Fibrillation. Medical Science Monitor International Medical Journal of Experimental & Clinical Research, 20, 463-470.
[8] Zhou, Q., Cao, H., Xu, Z., et al. (2017) Baseline Serum Globulin as a Predictor of the Recurrence of Lone Atrial Fibrillation after Radiofrequency Catheter Ablation. The Anatolian Journal of Cardiology, 17, 381-385.
[9] Shiozawa, T., Shimada, K., Sekita, G., et al. (2017) Left Atrial Appendage Volume and Plasma Docosahexaenoic Acid Levels Are Associated With Atrial Fibrillation Recurrence After Catheter Ablation. Cardiology Research, 8, 96-104.
[Google Scholar] [CrossRef] [PubMed]
[10] Nadadur, R.D., Broman, M.T., Boukens, B., et al. (2016) Pitx2 Modulates a Tbx5-Dependent Gene Regulatory Network to Maintain Atrial Rhythm. Science Translational Medicine, 8, 354ra115.
[Google Scholar] [CrossRef] [PubMed]
[11] Yue, L., Xie, J. and Nattel, S. (2011) Molecular Determinants of Cardiac Fibroblast Electrical Function and Therapeutic Implications for Atrial Fibrillation. Cardiovascular Research, 89, 744-753.
[Google Scholar] [CrossRef] [PubMed]
[12] Chiu, Y.-T., Wu, T.-J., Wei, H.-J., et al. (2005) Increased Extracellular Collagen Matrix in Myocardial Sleeves of Pulmonary Veins: An Additional Mechanism Facilitating Repetitive Rapid Activities in Chronic Pacing-Induced Sustained Atrial Fibrillation. Journal of Cardiovascular Electrophysiology, 16, 753.
[Google Scholar] [CrossRef] [PubMed]
[13] 董丽君, 汤宝鹏, 周贤惠, 等. 心房肌基质金属蛋白酶及其抑制剂、凋亡相关基因表达改变与增龄性心房颤动关系的研究[J]. 中国循环杂志, 2014(12): 1034-1038.
[14] Gallegocolon, E., Sampson, R.D., Sattler, S., et al. (2015) Cardiac-Restricted IGF-1Ea Overexpression Reduces the Early Accumulation of Inflammatory Myeloid Cells and Mediates Expression of Extracellular Matrix Remodelling Genes after Myocardial Infarction. Mediators of Inflammation, 2015, Article ID: 484357.
[15] Moe, G.W., Laurent, G., Doumanovskaia, L., et al. (2008) Matrix Metalloproteinase Inhibition Attenuates Atrial Remodeling and Vulnerability to Atrial Fibrillation in a Canine Model of Heart Failure. Journal of Cardiac Failure, 14, 768-776.
[Google Scholar] [CrossRef] [PubMed]
[16] Nakano, Y., Niida, S., Dote, K., Takenaka, S., Hirao, H., Miura, F., Ishida, M., Shingu, T., Sueda, T., Yoshizumi, M. and Chayama, K. (2004) Matrix Metalloproteinase-9 Contributes to Human Atrial Remodeling during Atrial Fibrillation. Journal of the American College of Cardiology, 43, 818-825.
[Google Scholar] [CrossRef] [PubMed]
[17] Bracey, N.A., Beck, P.L., Muruve, D.A., et al. (2013) The Nlrp3 Inflammasome Promotes Myocardial Dysfunction in Structural Cardiomyopathy through Interleukin-1β. Experimental Physiology, 98, 462.
[Google Scholar] [CrossRef] [PubMed]
[18] 李彬, 廖玉华, 程翔, 等. 卡维地洛对心肌梗死后大鼠心肌IL-1β表达及胶原沉积的影响[J]. 中华医学杂志, 2005, 85(6): 416-418.
[19] Verheule, S., Sato, T., Everett, T., et al. (2004) Increased Vulnerability to Atrial Fibrillation in Transgenic Mice with Selective Atrial Fibrosis Caused by Overexpression of TGF-β1. Circulation Research, 94, 1458-1465.
[Google Scholar] [CrossRef] 

为你推荐