红霉素联合甲氧氯普胺在急性胰腺炎中盲插鼻肠营养管的效果观察

The Effect Observation of Erythromycin Combined with Metoclopramide in the Treatment of Acute Pancreatitis in the Blind Insertion Nasal Nutrition Intestine

摘要: 目的：探讨红霉素联合甲氧氯普胺在急性胰腺炎中盲插鼻肠营养管的效果。方法：入院时将64例急性胰腺炎病人随机分为实验组和对照组，各32例，实验组为红霉素联合甲氧氯普胺、莫沙比利应用盲插鼻肠营养管，药物使用后一定时间内人为的将鼻肠管送入十二指肠乳头以下；其中男21例，女11例；对照组为只是盲插鼻肠营养管，没有使用药物和人为的送管，靠患者胃肠蠕动自行将鼻肠管送入十二指肠乳头以下，男17例，女15例。两组性别、年龄、血气分析、临床表现比较差异无统计学意义。均为入院后第2~3天执行，鼻肠管都使用复尔凯螺旋式，置管后摄片确定导管位置，排除患者入院时腹胀明显，腹内压监测 > 20 mmhg,，胃肠蠕动差。结果：红霉素联合甲氧氯普胺在急性胰腺炎中盲插鼻肠营养管，该方法操作简单、方便易行，而且对患者侵袭性小、价格低廉，插管成功率高，最重要的是推动急性胰腺炎患者早期肠内营养的顺利进行，提高了肠内营养的喂养率，降低了急性胰腺炎患者的并发症，缩短了患者住院时间，节省了住院费用，提高了病人满意度，差异有统计学意义(P < 0.05)。结论：红霉素联合甲氧氯普胺在急性胰腺炎中盲插鼻肠营养管,成功率高，操作简单，创伤小，护士、医生均可操作，可在临床上广泛推广使用。

Abstract: Objective: To investigate the effect of erythromycin combined with metoclopramide in the treat-ment of acute pancreatitis. Methods: 64 patients with acute pancreatitis were randomly divided into experimental group and control group (n = 32). Erythromycin combined with metoclopramide and mosapride were used in the experiment. After a certain period of time, the artificial intestine into the duodenal nipple below of which 21 males and 11 females; the control group is just blindly inserted nasal enteral feeding tube, without the use of drugs and artificial feeding tube, by the patient’s stomach Intestinal peristalsis into the nasal intestine into the duodenal nipple below, 17 males and 15 females. There were no statistically significant differences in sex, age, blood gas analysis and clinical manifestations between the two groups were admitted to the first 2 - 3 days after the implementation of the nasal intestine are used to repeat Kay screw, catheter placement to determine catheter placement, excluding patients admitted to abdominal distension, in-tra-abdominal pressure monitoring > 20 mmhg, poor gastrointestinal motility. Results: Erythro-mycin combined with metoclopramide in the treatment of acute pancreatitis. The method is simple, convenient and easy to operate. The method has the advantages of low invasiveness, low price, high success rate of intubation and most important is to promote the early enteral nutrition in patients with acute pancreatitis carried out to improve the feeding rate of enteral nutrition and reduce the complications of acute pancreatitis patients and shorten the hospital stay in patients, saving hospital costs and improve patient satisfaction. The difference was statistically significant (P < 0.05). Conclusion: Erythromycin combined with metoclopramide in acute pancreatitis in the blindly inserted nasolabial feeding tube, the success rate is high, simple operation, trauma, nurses, doctors can operate, can be widely used in clinical practice.