银翘散煎汁冲洗鼻腔治疗鼻咽癌放疗患者鼻腔粘连的疗效研究
Efficacy of Nasal Douche with Yinqiao San to Reduce or Salvage Nasal Adhesion after Nasopharyngeal Carcinoma Radiotherapy
DOI: 10.12677/ACM.2018.84067, PDF,   
作者: 王 楠, 曹建雄：湖南中医药大学第一附属医院肿瘤科，湖南 长沙
关键词: 鼻咽癌；鼻腔粘连；银翘散；鼻腔冲洗；Nasopharyngeal Neoplasm； Nasal Adhesions； Yinqiao San； Nasal Douche
摘要: 目的：探讨银翘散煎汁冲洗鼻腔治疗鼻咽癌放疗患者鼻腔粘连的疗效。方法：选取2017年1月~2017年12月我科收治的80例鼻咽癌放疗患者为研究对象，采用随机的方式将患者分为观察组和对照组，各40例。观察组采用银翘散煎汁进行鼻腔冲洗，对照组采用温生理盐水进行鼻腔冲洗。比较鼻腔黏膜反应的情况、鼻腔粘连比例及生活质量。结果：观察组鼻腔黏膜反应比对照组轻，鼻腔粘连低于对照组，差异有统计学意义(P < 0.05)。观察组生活质量评分比对照组低，差异有统计学意义(P < 0.05)。结论：采用银翘散煎汁冲洗鼻腔能够减轻鼻咽癌放疗患者的鼻腔黏膜反应，控制鼻腔粘连的发生，提高患者的生活质量。
Abstract: OBJECTIVE: To investigate the efficacy of Yinqiao San to reduce Nasal Adhesion after Nasopharyn-geal Carcinoma Radiotherapy. METHOD: 80 cases treated by our department from January to De-cember in 2017, which are divided into observation group and control group, with 40 cases re-spectively. Yin Qiao San is used for observation group, and normal saline for another. Nasal mucous membrane reaction, nasal adhesion ratio and quality of life are compared between two groups. RESULT: The nasal mucous membrane reaction and nasal adhesion ratio of observation group are significantly lower than that of control group (P < 0.05). Besides, the quality of life score in the observation group was lower than that in the control group, and the difference was statistically significant (P < 0.05). CONCLUSION: The use of Yinqiao San can reduce the nasal mucosal response of patients with nasopharyngeal carcinoma radiotherapy, control the occurrence of nasal adhesions, and improve the quality of life of patients.
文章引用：王楠, 曹建雄. 银翘散煎汁冲洗鼻腔治疗鼻咽癌放疗患者鼻腔粘连的疗效研究[J]. 临床医学进展, 2018, 8(4): 400-403. https://doi.org/10.12677/ACM.2018.84067

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