散发型克雅病临床诊断1例合并文献复习
A Case of Sporadic Creutzfeldt-Jakob Disease and Literature Review
DOI: 10.12677/ACM.2018.87112, PDF,   
作者: 潘月飞, 张校双:中国人民解放军第251医院感染疾病科,河北 张家口;田高波, 徐冬清:中国人民解放军第251医院医务处质量控制科,河北 张家口
关键词: 克雅病早期诊断治疗经验Creutzfeldt-Jakob Disease Earlier Diagnosis Treatment Experiences
摘要: 目的:总结1例克雅病患者的治疗经验并进行文献复习。方法:通过对我院收治的1名克雅病患者治疗过程进行观察,总结克雅病的治疗经验并进行文献复习。结论:克雅病是朊病毒感染引起的一种死亡率极高的疾病,如能在疾病发生早期,明确克雅病的诊断对预防其医源性传播以及及时开展对症治疗具有重要意义。
Abstract: Objective: To summarize the treatment experience of 1 case of Creutzfeldt-Jakob disease and do some literature review. Methods: By the observation of a Creutzfeldt-Jakob patient, we summarize the experiences of Creutzfeldt-Jakob disease treatment and review the literature. Conclusion: Creutzfeldt-Jakob disease is a infectious disease caused by prion with higher mortality, earlier di-agnostic is important for preventing iatrogenic transmission and symptomatic treatment.
文章引用:潘月飞, 张校双, 田高波, 徐冬清. 散发型克雅病临床诊断1例合并文献复习[J]. 临床医学进展, 2018, 8(7): 668-671. https://doi.org/10.12677/ACM.2018.87112

参考文献

[1] Prince, L.A., Mann, D. and Reilly, T. (2006) Creutzfeldt-Jakob Disease: An Emergency Department Presentation of a Rare Disease. Journal of Emergency Medicine, 31, 41-44. [Google Scholar] [CrossRef] [PubMed]
[2] Krasnianski, A., Kaune, J., Jung, K., et al. (2014) First Symptom and Initial Diagnosis in Sporadic CJD Patients in Germany. Journal of Neurology, 261, 1811-1817. [Google Scholar] [CrossRef] [PubMed]
[3] 李洁, 吴大方, 刘晓宇, 等. 克雅病辅助检查的研究进展[J]. 临床荟萃, 2012, 27(3): 260-263.
[4] Knight, R. (2006) Creutzfeldt-Jakob Disease: A Rare Cause of Dementia in El-derly Persons. Clinical Infectious Diseases, 43, 340-346. [Google Scholar] [CrossRef] [PubMed]
[5] Lee, J., Hyeon, J.W., Kim, S.Y., et al. (2015) Review: Laboratory Diagnosis and Surveillance of Creutzfeldt-Jakob Disease. Journal of Medical Virology, 87, 175-186. [Google Scholar] [CrossRef] [PubMed]
[6] Puoti, G., Bizzi, A., Forloni, G., et al. (2012) Sporadic Human Prion Diseases: Molecular Insights and Diagnosis. Lancet Neurology, 11, 618-628. [Google Scholar] [CrossRef
[7] 王国强, 尹维民, 张微微. 克雅氏病临床诊断1例[J]. 解放军医学杂志, 2008, 33(3): 358.
[8] Shiga, Y., Miyazawa, K., Sato, S., et al. (2004) Diffusion-Weighted MRI Ab-normalities as an Early Diagnostic Marker for Creutzfeldt-Jakob Disease. Neurology, 63, 443-449. [Google Scholar] [CrossRef
[9] Harrington, M.G., Merril, C.R., Asher, D.M., et al. (1986) Abnormal Proteins in the Cerebrospinal Fluid of Patients with Creutzfeldt-Jakob Disease. New England Journal of Medicine, 315, 279-283. [Google Scholar] [CrossRef
[10] Will, R.G., Alperovitch, A., Poser, S., et al. (1998) De-scriptive Epidemiology of Creutzfeldt-Jakob Disease in Six European Countries, 1993-1995. EU Collaborative Study Group for CJD. Annals of Neurology, 43, 763-767. [Google Scholar] [CrossRef] [PubMed]
[11] Collins, S.J., Mcglade, A., Boyd, A., et al. (2010) 14-3-3 Protein Detection and Sporadic CJD: The Status Quo Serves Well While Awaiting Progress. Journal of Neurology Neurosur-gery & Psychiatry, 81, 1181. [Google Scholar] [CrossRef] [PubMed]
[12] Gmitterova, K., Heinemann, U., Bodemer, M., et al. (2009) 14-3-3 CSF Levels in Sporadic Creutzfeldt-Jakob Disease Differ across Molecular Subtypes. Neurobiology of Aging, 30, 1842-1850. [Google Scholar] [CrossRef] [PubMed]
[13] Pennington, C., Chohan, G., Mackenzie, J., et al. (2009) The Role of Cerebrospinal Fluid Proteins as Early Diagnostic Markers for Sporadic Creutzfeldt-Jakob Disease. Neuroscience Letters, 455, 56-59. [Google Scholar] [CrossRef] [PubMed]
[14] Hamlin, C., Puoti, G., Berri, S., et al. (2012) A Comparison of Tau and 14-3-3 Protein in the Diagnosis of Creutzfeldt-Jakob Disease. Neurology, 79, 547-552. [Google Scholar] [CrossRef
[15] van Harten, A.C., Kester, M.I., Visser, P.J., et al. (2011) Tau and P-Tau as CSF Biomarkers in Dementia: A Meta-Analysis. Clinical Chemistry and Laboratory Medicine, 49, 353-366. [Google Scholar] [CrossRef
[16] Bahl, J.M., Heegaard, N.H., Falkenhorst, G., et al. (2009) The Diagnostic Efficiency of Biomarkers in Sporadic Creutzfeldt-Jakob Disease Compared to Alzheimer’s Disease. Neurobiology of Aging, 30, 1834-1841. [Google Scholar] [CrossRef] [PubMed]