持续性姿势–知觉性头晕的研究进展
Research Progress of Persistent Posture-Perceived Dizziness
DOI: 10.12677/ACM.2018.88121, PDF,   
作者: 王淑青, 阎文静, 王海萍：青岛大学附属医院神经内科，山东 青岛；王春霞：青岛精神卫生中心，山东 青岛
关键词: 持续性姿势–知觉性头晕；发病机制；临床治疗；Persistent Posture-Perceived Dizziness (PPPD)； Pathogenesis； Clinical Treatment
摘要: 持续性姿势–知觉性头晕是一种常见的功能障碍疾病，发病率高，误诊率高。本文综述持续性姿势–知觉性头晕的研究进展，阐述其临床特征和可能的发病机制，总结其诊断和治疗，旨在提高临床医师对该病的认识。应深入研究持续性姿势–知觉性头晕的发病机制，尤其是分子病理机制。目前持续性姿势–知觉性头晕的药物治疗主要集中在神经递质5-羟色胺上，需要更多的研究来发现其他作用靶点对该疾病的疗效，从而为临床治疗提供更多选择。
Abstract: Persistent posture-perceived dizziness is a common disorder with high morbidity and high mis-diagnosis rates. This review expounds its clinical features and possible pathogenesis, summarizes the diagnosis and treatment, and aims to improve clinicians’ understanding of the disease. In-depth study should be carried out on the pathogenesis of persistent posture-conscious dizziness, especially molecular pathology. The current drug therapy of persistent posture-perceived dizziness is mainly concentrated on the neuro-transmitter serotonin; more research is needed to find out the therapeutic effect of dopamine and other targets on the disease, so as to provide more choices for clinical treatment.
文章引用：王淑青, 阎文静, 王春霞, 王海萍. 持续性姿势–知觉性头晕的研究进展[J]. 临床医学进展, 2018, 8(8): 719-725. https://doi.org/10.12677/ACM.2018.88121

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