|
[1]
|
Singer, M., Deutschman, C.S., Seymour, C.W., et al. (2016) The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA, 315, 801-810. [Google Scholar] [CrossRef] [PubMed]
|
|
[2]
|
(2017) WHA Resolution A70/13—Improving the Prevention, Diagnosis and Clinical Management of Sepsis. WHO, Geneva, Swit-zerland.
|
|
[3]
|
Bloos, F., Thomas-Rüddel, D., Rüddel, H., Engel, C., Schwarzkopf, D., Marshall, J.C., et al. (2014) Im-pact of Compliance with Infection Management Guidelines on Outcome in Patients with Severe Sepsis: A Prospective Observational Multi-Center Study. Crit Care, 18, R42.
|
|
[4]
|
Angus, D.C. and van der Poll, T. (2013) Severe Sepsis and Septic Shock. New England Journal of Medicine, 369, 840-851. [Google Scholar] [CrossRef]
|
|
[5]
|
Bone, R.C., Grodzin, C.J. and Balk, R.A. (1997) Sepsis: A New Hypothesis for Pathogenesis of the Disease Process. Chest, 112, 235-243. [Google Scholar] [CrossRef] [PubMed]
|
|
[6]
|
Liuzzi, J.P. and Cousins, R.J. (2004) Mammalian Zinc Transporters. Annual Review of Nutrition, 24, 151-172. [Google Scholar] [CrossRef] [PubMed]
|
|
[7]
|
Lukacik, M., Thomas, R.L. and Aranda, J.V. (2008) A Meta-Analysis of the Effects of Oral Zinc in the Treatment of Acute and Persistent Diarrhea. Pediatrics, 121, 326-336. [Google Scholar] [CrossRef] [PubMed]
|
|
[8]
|
King, L.E., Frentzel, J.W., Mann, J.J. and Fraker, P.J. (2005) Chronic Zinc Deficiency in Mice Disrupted T Cell Lymphopoiesis and Erythropoiesis While B Cell Lymphopoiesis and Myelopoiesis Were Maintained. Journal of the American College of Nutrition, 24, 494-502. [Google Scholar] [CrossRef] [PubMed]
|
|
[9]
|
Prasad, A.S., Meftah, S., Abdallah, J., Kaplan, J., Brewer, G.J., Bach, J.F. and Dardenne, M. (1988) Serum Thymulin in Human Zinc Deficiency. Journal of Clinical Investigation, 82, 1202-1210. [Google Scholar] [CrossRef]
|
|
[10]
|
Mayer, L.S., Uciechowski, P., Meyer, S., Schwerdtle, T., Rink, L. and Haase, H. (2014) Differential Impact of Zinc Deficiency on Phagocytosis, Oxidative Burst, and Production of Pro-Inflammatory Cytokines by Human Monocytes. Metallomics, 6, 1288-1295. [Google Scholar] [CrossRef] [PubMed]
|
|
[11]
|
Dardenne, M., Pléau, J.M., Nabarra, B., Lefrancier, P., Derrien, M., Choay, J. and Bach, J.F. (1982) Contribution of Zinc and Other Metals to the Biological Activity of the Serum Thymic Factor. Proceedings of the National Academy of Sciences of USA, 79, 5370-5373. [Google Scholar] [CrossRef] [PubMed]
|
|
[12]
|
Incefy, G.S., Mertelsmann, R., Yata, K., Dardenne, M., Bach, J.F. and Good, R.A. (1980) Induction of Differentiation in Human Marrow T Cell Precursors by the Synthetic Serum Thymic Factor, FTS. Clinical & Experimental Immunology, 40, 396-406.
|
|
[13]
|
Hasan, R., Rink, L. and Haase, H. (2013) Zinc Signals in Neutrophil Granulocytes Are Required for the Formation of Neutrophil Extracellular Traps. Innate Immunity, 19, 253-264. [Google Scholar] [CrossRef] [PubMed]
|
|
[14]
|
Kaltenberg, J., Plum, L.M., Ober-Blbaum, J.L., Hnscheid, A., Rink, L. and Haase, H. (2010) Zinc Signals Promote IL-2-Dependent Proliferation of T Cells. European Journal of Immunology, 40, 1496-1503. [Google Scholar] [CrossRef] [PubMed]
|
|
[15]
|
I. Wessels, R.J. (2015) Cousins Zinc Dyshomeostasis during Polymi-crobial Sepsis in Mice Involves Zinc Transporter Zip14 and Can Be Overcome by Zinc Supplementation. American Journal of Physiology-Gastrointestinal and Liver Physiology, 309, G768-G778. [Google Scholar] [CrossRef] [PubMed]
|
|
[16]
|
Rech, M., et al. (2014) Heavy Metal in the Intensive Care Unit: A Review of Current Literature on Trace Element Supplementation in Critically Ill Patients. Nutrition in Clinical Practice, 29, 78-89. [Google Scholar] [CrossRef] [PubMed]
|
|
[17]
|
Knoell, D.L., et al. (2009) Zinc Deficiency Increases Organ Damage and Mortality in a Murine Model of Polymicrobial Sepsis. Critical Care Medicine, 37, 1380-1388. [Google Scholar] [CrossRef]
|
|
[18]
|
Shea-Budgell, M., et al. (2006) Marginal Zinc Deficiency Increased the Susceptibility to Acute Lipopolysaccharide-Induced Liver Injury in Rats. Experimental Biology and Medicine (Maywood), 231, 553-558. [Google Scholar] [CrossRef] [PubMed]
|
|
[19]
|
Crowell, K.T., et al. (2016) Marginal Dietary Zinc Deprivation Augments Sepsis-Induced Alterations in Skeletal Muscle TNF-α But Not Protein Synthesis. Physiological Reports, 4, pii: e13017.
|
|
[20]
|
Skrovanek, S., et al. (2014) Zinc and Gastrointestinal Disease. World Journal of Gastrointestinal Pathophysiology, 5, 496-513. [Google Scholar] [CrossRef] [PubMed]
|
|
[21]
|
Crouser, E., et al. (2008) Sepsis: Links between Pathogen Sensing and Organ Damage. Current Pharmaceutical Design, 14, 1840-1852. [Google Scholar] [CrossRef] [PubMed]
|
|
[22]
|
Abraham, E. (2003) Nuclear Factor-kappaB and Its Role in Sepsis-Associated Organ Failure. The Journal of Infectious Diseases, 187, S364-S369. [Google Scholar] [CrossRef] [PubMed]
|
|
[23]
|
Liu, M.J., et al. (2013) ZIP8 Regulates Host Defense through Zinc-Mediated Inhibition of NF-κB. Cell Reports, 3, 386-400. [Google Scholar] [CrossRef] [PubMed]
|
|
[24]
|
von Bülow, V., et al. (2007) Zinc-Dependent Suppression of TNF-alpha Production Is Mediated by Protein Kinase A-Induced Inhibition of Raf-1: I kappa B kinase Beta, and NF-kappa B. The Journal of Immunology, 179, 4180-4186. [Google Scholar] [CrossRef] [PubMed]
|
|
[25]
|
Lork, M., Verhelst, K. and Beyaert, R. (2017) CYLD, A20 and OTULIN Deubiquitinases in NF-κB Signaling and Cell Death: So Similar, Yet So Different. Cell Death & Differentia-tion, 24, 1172-1183. [Google Scholar] [CrossRef] [PubMed]
|
|
[26]
|
Li, C., et al. (2015) Maternal High-Zinc Diet At-tenuates Intestinal Inflammation by Reducing DNA Methylation and Elevating H3K9 Acetylation in the A20 Promoter of Offspring Chicks. The Journal of Nutritional Biochemistry, 26, 173-183. [Google Scholar] [CrossRef] [PubMed]
|
|
[27]
|
Arraes, S.M., et al. (2006) Impaired Neutrophil Chemotaxis in Sepsis Associates with GRK Expression and Inhibition of Actin Assembly and Tyrosine Phosphorylation. Blood, 108, 2906-2913. [Google Scholar] [CrossRef] [PubMed]
|
|
[28]
|
Kovach, M.A. and Standiford, T.J. (2012) The Function of Neutrophils in Sepsis. Current Opinion in Infectious Diseases, 25, 321-327. [Google Scholar] [CrossRef]
|
|
[29]
|
Hasan, R., Rink, L. and Haase, H. (2016) Chelation of Free Zn2+ Impairs Chemotaxis, Phagocytosis, Oxidative Burst, Degranulation, and Cytokine Production by Neutrophil Granulocytes. Biological Trace Element Research, 171, 79-88. [Google Scholar] [CrossRef] [PubMed]
|
|
[30]
|
Watanabe, N., et al. (2016) Sepsis Induces Incomplete M2 Phe-notype Polarization in Peritoneal Exudate Cells in Mice. Journal of Intensive Care, 4, 6. [Google Scholar] [CrossRef] [PubMed]
|
|
[31]
|
Muzzioli, M., et al. (2007) Zinc Improves the Development of Human CD34+ Cell Progenitors towards Natural Killer Cells and Induces the Expression of GATA-3 Transcription Factor. The International Journal of Biochemistry & Cell Biology, 39, 955-965. [Google Scholar] [CrossRef] [PubMed]
|
|
[32]
|
Newton, B., Ballambattu, V.B., Bosco, D.B., Gopalakrishna, S.M. and Subash, C.P. (2017) Efficacy of Zinc Supplementation on Serum Calprotectin, Inflammatory Cytokines and Outcome in Neonatal Sepsis—A Randomized Controlled Trial. The Journal of Maternal-Fetal & Neonatal Medicine, 30, 1627-1631. [Google Scholar] [CrossRef] [PubMed]
|
|
[33]
|
Newton, B., Bhat, B.V., Bosco Dhas, B., Mondal, N. and Gopalakrishna, S.M. (2016) Effect of Zinc Supplementation on Early Outcome of Neonatal Sepsis—A Randomized Controlled Trial. Indian Journal of Pediatrics, 83, 289-293. [Google Scholar] [CrossRef] [PubMed]
|
|
[34]
|
Newton, B., Bhat, B.V., Bosco Dhas, B., Christina, C., Gopala-krishna, S.M. and Subhash Chandra, P. (2018) Short Term Oral Zinc Supplementation among Babies with Neonatal Sepsis for Reducing Mortality and Improving Outcome—A Double-Blind Randomized Controlled Trial. Indian Journal of Pediatrics, 85, 5-9. [Google Scholar] [CrossRef] [PubMed]
|
|
[35]
|
Mehta, K., Bhatta, N.K., Majhi, S., Shrivastava, M.K. and Singh, R.R. (2013) Oral Zinc Supplementation for Reducing Mortality in Probable Neonatal Sepsis: A Double Blind Ran-domized Placebo Controlled Trial. Indian Pediatrics, 50, 390-393. [Google Scholar] [CrossRef] [PubMed]
|
|
[36]
|
Ganatra, H.A., Varisco, B.M., Harmon, K., Lahni, P., Opoka, A. and Wong, H.R. (2017) Zinc Supplementation Leads to Immune Modulation and Improved Survival in a Juvenile Model of Murine Sepsis. Innate Immunity, 23, 67-76. [Google Scholar] [CrossRef] [PubMed]
|
|
[37]
|
Nowak, J.E., Harmon, K., Caldwell, C.C. and Wong, H.R. (2012) Prophylactic Zinc Supplementation Reduces Bacterial Load and Improves Survival in a Murine Model of Sepsis. Pedi-atric Critical Care Medicine, 13, e323-e329.
|
|
[38]
|
Hoeger, J., Simon, T.-P., Doemming, S., Thiele, C., Marx, G., Schuerholz, T. and Haase, H. (2015) Alterations in Zinc Binding Capacity, Free Zinc Levels and Total Serum Zinc in a Porcine Model of Sepsis. BioMetals, 28, 693-700. [Google Scholar] [CrossRef] [PubMed]
|
|
[39]
|
Jang, J.Y., Shim, H., Lee, S.H. and Lee, J.G. (2014) Serum Se-lenium and Zinc Levels in Critically Ill Surgical Patients. Journal of Critical Care, 29, 317.e5-317.e8. [Google Scholar] [CrossRef] [PubMed]
|
|
[40]
|
Trame, S., Wessels, I., Haase, H. and Rink, L. (2018) A Short 18 Items Food Frequency Questionnaire Biochemically Validated to Estimate Zinc Status in Humans. Journal of Trace Elements in Medicine and Biology, 49, 285-295. [Google Scholar] [CrossRef] [PubMed]
|
|
[41]
|
Wessels, I. and Cousins, R.J. (2015) Zinc Dyshomeostasis during Polymicrobial Sepsis in Mice Involves Zinc Transporter Zip14 and Can Be Overcome by Zinc Supplementation. American Journal of Physiology-Gastrointestinal and Liver Physiology, 309, G768-G778. [Google Scholar] [CrossRef] [PubMed]
|