口周肌阵挛伴失神临床分析
Clinical Analysis of Perioral Myoclonia with Absence
DOI: 10.12677/IJPN.2018.74007, PDF,   
作者: 高 伟：北京大学首钢医院神经内科，北京
关键词: 口周肌阵挛伴失神；癫痫；脑电图；Perioral Myoclonia with Absences； Epilepsy； EEG
摘要: 目的：探讨口周肌阵挛伴失神的临床特点和发病机制。方法：分析其临床特点、脑电图表现和治疗。结果：发作表现为口周肌肉节律性抽动，伴有短暂意识障碍，发作次数较频繁。发作期脑电图特征为阵发广泛性2.5 Hz棘慢波，发作间期脑电图、头颅影像学均正常。给予丙戊酸钠治疗有显效。结论：口周肌阵挛伴失神是一种少见的特发性全面性癫痫综合征，诊断依靠详细的发作症状和脑电图表现。
Abstract: Objective: To identify the clinical characteristics and electro-encephalographic (EEG) features of perioral myoclonia with absence (PMA). Methods: A case with PMA was reported in this study. Clinical manifestations, Video-EEG, treatment and prognosis were analyzed. Results: Perioral myoclonia consists of rhythmic protrusion of the lips, twitching of the corners of the mouth ac-companied by disturbance of consciousness. His neurological examination was normal. The background activity on the interictal EEG was normal. The ictal EEG characteristics were generalized discharges of 2.5 Hz spikes and slow wave burst. Brain MRI was also normal. Sodium valproate has a significant effect to cure PMA. Conclusions: PMA is a rare type of idiopathic generalized epilepsy syndrome characterized by absences with ictal motor symptoms of perioral myoclonia, whose correct diagnosis is obtained on the basis of full manifestations in detail and Video-EEG monitoring.
文章引用：高伟. 口周肌阵挛伴失神临床分析[J]. 国际神经精神科学杂志, 2018, 7(4): 42-45. https://doi.org/10.12677/IJPN.2018.74007

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