基于多元分析的化学计量学方法用于pKa测定的研究
Investigation of Chemometrics Methods in pKa Determination Based on Multivariate Data Analysis
DOI: 10.12677/AAC.2018.84025, PDF,    国家自然科学基金支持
作者: 程 翰, 张先正：武汉大学化学与分子科学学院，湖北 武汉
关键词: 多元分析；化学计量学；教学研究；Multivariate Data Analysis； Chemometrics； Teaching Research
摘要: 无机及分析化学基础实验是我院开设的一门本科实验课程，在本课程中引入化学计量学中多元分析的方法用于实验教学，培养学生了解和使用分析统计工具的能力，对学生的综合素质的提高是有重要意义的。 我们据此设计了一组实验，在选定的具有多光谱重叠的酸碱指示剂质子平衡体系中，通过UV-Vis分光光度法来测定酸碱指示剂体系的吸光度，同时测定其pH值，使用化学计量学计算其解离常数，并与经典分析方法进行比较，探讨其优缺点。
Abstract: A new approach to teaching basic experimental inorganic and analytical chemistry offered by our college was presented. The introduction of chemometrics method based on multivariate data analysis was of great significance to improve the ability of undergraduate students in under-standing and use of analytical technology and statistical tools. Based on this, we designed a set of experiments to determine the absorbance of the acid-base indicators with multi-spectral overlap. The pH values were also determined. The dissociation constants were calculated by chemometrics and classical analytical methods. Moreover, the advantages and shortages were also compared and discussed.
文章引用：程翰, 张先正. 基于多元分析的化学计量学方法用于pKa测定的研究[J]. 分析化学进展, 2018, 8(4): 204-212. https://doi.org/10.12677/AAC.2018.84025

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