LncRNA在肺癌中的研究进展
Advances of LncRNA in Lung Cancer
DOI: 10.12677/ACM.2018.810152, PDF,   
作者: 李浩然, 高 健, 丁建勇:复旦大学附属中山医院胸外科,上海;李泽环:复旦大学附属中山医院普通外科,上海
关键词: 肺癌LncRNA转移自噬肿瘤免疫Lung Cancer LncRNA Metastasis Autophagy Tumor Immunity
摘要: 肺癌是世界上致死率第一的癌症,主要原因在于肺癌的侵袭转移和复发。lncRNA是一类非编码RNA分子,研究发现其与包括肺癌在内的多种肿瘤密切相关。lncRNA不仅参与肺癌组织细胞的侵袭、迁移和增殖过程,并且与细胞自噬、肿瘤免疫联系紧密。因此,研究lncRNA与肺癌的关系具有重要意义。
Abstract: Lung cancer is the most leading cancer death worldwide mainly due to the high metastasis and recurrence rate of lung cancer. LncRNA is non-coding RNA molecule that cannot translate into protein, which is associated with many carcinomas including lung cancer. LncRNA is not only in-volved in the invasion, migration and proliferation of lung cancer cells, but also close to cell au-tophagy and tumor immunity. Therefore, it is of great significance to study the relation between lncRNA and lung cancer.
文章引用:李浩然, 李泽环, 高健, 丁建勇. LncRNA在肺癌中的研究进展[J]. 临床医学进展, 2018, 8(10): 915-921. https://doi.org/10.12677/ACM.2018.810152

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