基于机器学习的预测模型对抑郁症的研究进展
Research Progress on Predictive Models Based on Machine Learning for Depression
DOI: 10.12677/AP.2019.91005, PDF,   
作者: 杨兵兵, 李俊男, 何 鸿, 冯秋阳:西南大学心理学部,认知与人格教育部重点实验室,重庆
关键词: 抑郁机器学习预测模型Depression Machine Learning Predictive Model
摘要: 随着机器学习方法的兴起,越来越多的研究将预测模型纳入神经领域的研究中,尤其在抑郁症的研究中做了大量工作,但是存在研究结果稳定性的差异。目前通过机器学习的方法实现对抑郁症个体差异的预测以及治疗。本文总结了:1) 预测模型的构建;2) 抑郁症预测的研究现状;3) 预测中存在的问题和当前的总结;4) 对抑郁症的诊断和意义的展望。总体实现了通过预测模型实现对抑郁症的诊断,但是在神经预测的研究的一致性上需要更多的证据或者运用元分析的方法实现。未来结合临床提高抑郁症的诊断和治疗。
Abstract: With the rise of machine learning methods, more and more studies have incorporated predictive models into the field of neuroscience research, especially in the study of depression, but there is an interpretation of the differences in the stability of research results. The prediction and treat-ment of individual differences in depression are currently achieved through machine learning. This paper summarizes: 1) the construction of predictive models; 2) the current research status of depression prediction; 3) the problems and current conclusions in the prediction; 4) the diagnosis and significance of depression. The overall diagnosis of depression is achieved through predictive models, but more evidence is needed for the consistency of neural prediction studies or by meta-analysis. In the future, study should be combined with clinical to improvement the diagnosis and treatment of depression.
文章引用:杨兵兵, 李俊男, 何鸿, 冯秋阳 (2019). 基于机器学习的预测模型对抑郁症的研究进展. 心理学进展, 9(1), 34-40. https://doi.org/10.12677/AP.2019.91005

参考文献

[1] Ball, T. M., Goldsteinpiekarski, A. N., Gatt, J. M., & Williams, L. M. (2017). Quantifying Person-Level Brain Network Functioning to Facilitate Clinical Translation. Translational Psychiatry, 7, e1248.
[CrossRef] [PubMed]
[2] Blazer, D. G., Kessler, R. C., Mcgonagle, K. A., & Swartz, M. S. (1994). The Prevalence and Distribution of Major Depression in a National Community Sample: The National Comorbidity Survey. American Journal of Psychiatry, 151, 979.
[CrossRef] [PubMed]
[3] Ciric, R., Wolf, D. H., Power, J. D., Roalf, D. R., Baum, G., Ruparel, K., Shinohara, R. T., Elliott, M. A., Eickhoff, S. B., & Davatzikos, C. (2017). Benchmarking of Participant-Level Confound Regression Strategies for the Control of Motion Artifact in Studies of Functional Connectivity. Neuroimage, 154.
[CrossRef] [PubMed]
[4] Costafreda, S. G., Chu, C., Ashburner, J., & Fu, C. H. Y. (2009). Prognostic and Diagnostic Potential of the Structural Neuroanatomy of Depression. Plos One, 4, e6353.
[CrossRef] [PubMed]
[5] Costafreda, S. G., Khanna, A., Mourao-Miranda, J., & Fu, C. H. (2009). Neural Correlates of Sad Faces Predict Clinical Remission to Cognitive Behavioural Therapy in Depression. Neuroreport, 20, 637-641.
[CrossRef
[6] Crane, N. A., Jenkins, L. M., Bhaumik, R., Dion, C., Gowins, J. R., Mickey, B. J., Zubieta, J. K., & Langenecker, S. A. (2017). Multidimensional Prediction of Treatment Response to Antidepressants with Cognitive Control and Functional MRI. Brain, 140, 472-486.
[CrossRef] [PubMed]
[7] Dichter, G. S., Felder, J. N., & Smoski, M. J. (2010). The Effects of Brief Behavioral Activation Therapy for Depression on Cognitive Control in Affective Contexts: An fMRI Investigation. Journal of Affective Disorders, 126, 236.
[CrossRef] [PubMed]
[8] Dichter, G. S., Gibbs, D., & Smoski, M. J. (2015). A Systematic Review of Relations between Resting-State Functional-MRI and Treatment Response in Major Depressive Disorder. Journal of Affective Disorders, 172, 8-17.
[CrossRef] [PubMed]
[9] Ferrari, A. J., Charlson, F. J., Norman, R. E., Patten, S. B., Freedman, G., Murray, C. J., Vos, T., & Whiteford, H. A. (2013). Burden of Depressive Disorders by Country, Sex, Age, and Year: Findings from the Global Burden of Disease Study 2010. PLOS Medicine, 10, e1001547.
[CrossRef] [PubMed]
[10] Gabrieli, J. D. E., Ghosh, S. S., & Whitfieldgabrieli, S. (2015). Prediction as a Humanitarian and Pragmatic Contribution from Human Cognitive Neuroscience. Neuron, 85, 11-26.
[11] Guyon, I., & Elisseeff, A. (2003). An Introduction to Variable and Feature Selection. Journal of Machine Learning Research, 3, 1157-1182.
[12] Gyurak, A., Patenaude, B., Korgaonkar, M. S., Grieve, S. M., Williams, L. M., & Etkin, A. (2016). Frontoparietal Activation during Response Inhibition Predicts Remission to Antidepressants in Patients with Major Depression. Biological Psychiatry, 79, 274.
[CrossRef] [PubMed]
[13] Hahn, T., Kircher, T., Straube, B., Wittchen, H. U., Konrad, C., Ströhle, A., Wittmann, A., Pfleiderer, B., Reif, A., & Arolt, V. (2015). Predicting Treatment Response to Cognitive Behavioral Therapy in Panic Disorder with Agoraphobia by Integrating Local Neural Information. JAMA Psychiatry, 72, 68.
[CrossRef] [PubMed]
[14] Jia, Z., Huang, X., Wu, Q., Zhang, T., Lui, S., Zhang, J., Amatya, N., Kuang, W., Chan, R. C., & Kemp, G. J. (2010). High-Field Magnetic Resonance Imaging of Suicidality in Patients with Major Depressive Disorder. American Journal of Psychiatry, 167, 1381.
[CrossRef] [PubMed]
[15] Kievit, R. A., Brandmaier, A. M., Ziegler, G., van Harmelen, A. L., Smm, D. M., Moutoussis, M., Goodyer, I. M., Bullmore, E., Jones, P. B., & Fonagy, P. (2017). Developmental Cognitive Neuroscience Using Latent Change Score Models: A Tutorial and Applications. Developmental Cognitive Neuroscience, 33, 99-117.
[CrossRef
[16] Langenecker, S. A., Kennedy, S. E., Guidotti, L. M., Briceno, E. M., Own, L. S., Hooven, T., Young, E. A., Akil, H., Noll, D. C., & Zubieta, J. K. (2007). Frontal and Limbic Activation during Inhibitory Control Predicts Treatment Response in Major Depressive Disorder. Biological Psychiatry, 62, 1272-1280.
[CrossRef] [PubMed]
[17] Liang, M. J., Zhou, Q., Yang, K. R., Yang, X. L., Fang, J., Chen, W. L., & Huang, Z. (2013). Identify Changes of Brain Regional Homogeneity in Bipolar Disorder and Unipolar Depression Using Resting-State fMRI. PLoS ONE, 8, e79999.
[CrossRef] [PubMed]
[18] Liu, F., Guo, W., Liu, L., Long, Z., Ma, C., Xue, Z., Wang, Y., Li, J., Hu, M., & Zhang, J. (2013). Abnormal Amplitude Low-Frequency Oscillations in Medication-Naive, First-Episode Patients with Major Depressive Disorder: A Resting-State fMRI Study. Journal of Affective Disorders, 146, 401-406.
[CrossRef] [PubMed]
[19] López-Solà, M., Pujol, J., Hernández-Ribas, R., Harrison, B. J., Contreras-Rodríguez, O., Soriano-Mas, C., Deus, J., Ortiz, H., Menchón, J. M., & Vallejo, J. (2010). Effects of Duloxetine Treatment on Brain Response to Painful Stimulation in Major Depressive Disorder. Neuropsychopharmacology, 35, 2305.
[CrossRef] [PubMed]
[20] Mayberg, H. S., Brannan, S. K., Mahurin, R. K., Jerabek, P. A., Brickman, J. S., Tekell, J. L., Silva, J. A., Mcginnis, S., Glass, T. G., & Martin, C. C. (1997). Cingulate Function in Depression: A Potential Predictor of Treatment Response. Neuroreport, 8, 1057-1061.
[CrossRef] [PubMed]
[21] Menon, V., & Uddin, L. Q. (2010). Saliency, Switching, Attention and Control: A Network Model of Insula Function. Brain Structure & Function, 214, 655-667.
[CrossRef] [PubMed]
[22] Miller, J. M., Schneck, N., Siegle, G. J., Chen, Y., Ogden, R. T., Kikuchi, T., Oquendo, M. A., Mann, J. J., & Parsey, R. V. (2013). fMRI Response to Negative Words and SSRI Treatment Outcome in Major Depressive Disorder: A Preliminary Study. Psychiatry Research, 214, 296-305.
[CrossRef] [PubMed]
[23] Pardoe, H. R., Kucharsky, H. R., & Kuzniecky, R. (2016). Motion and Morphometry in Clinical and Nonclinical Populations. Neuroimage, 135, 177.
[CrossRef] [PubMed]
[24] Pizzagalli, D. A. (2011). Frontocingulate Dysfunction in Depression: Toward Biomarkers of Treatment Response. Neuropsychopharmacology Official Publication of the American College of Neuropsychopharmacology, 36, 183-206.
[CrossRef] [PubMed]
[25] Pizzagalli, D., Pascualmarqui, R. D., Nitschke, J. B., Oakes, T. R., Larson, C. L., Abercrombie, H. C., Schaefer, S. M., Koger, J. V., Benca, R. M., & Davidson, R. J. (2014). Anterior Cingulate Activity as a Predictor of Degree of Treatment Response in Major Depression: Evidence from Brain Electrical Tomography Analysis. American Journal of Psychiatry, 158, 405.
[CrossRef] [PubMed]
[26] Rizvi, S. J., Salomons, T. V., Konarski, J. Z., Downar, J., Giacobbe, P., Mcintyre, R. S., & Kennedy, S. H. (2013). Neural Response to Emotional Stimuli Associated with Successful Antidepressant Treatment and Behavioral Activation. Journal of Affective Disorders, 151, 573-581.
[CrossRef] [PubMed]
[27] Sacher, J., Neumann, J., & Fünfstück, T. (2012). Mapping the Depressed Brain: A Meta-Analysis of Structural and Functional Alterations in Major Depressive Disorder. Journal of Affective Disorders, 140, 142-148.
[CrossRef] [PubMed]
[28] Sheline, Y. I., Price, J. L., Yan, Z., & Mintun, M. A. (2010). Resting-State Functional MRI in Depression Unmasks Increased Connectivity between Networks via the Dorsal Nexus. Proceedings of the National Academy of Sciences of the United States of America, 107, 11020.
[CrossRef] [PubMed]
[29] Shen, X., Finn, E. S., Scheinost, D., Rosenberg, M. D., Chun, M. M., Papademetris, X., & Constable, R. T. (2017). Using Connectome-Based Predictive Modeling to Predict Individual Behavior from Brain Connectivity. Nature Protocols, 12, 506.
[CrossRef] [PubMed]
[30] Stimpson, N., Agrawal, N., & Lewis, G. (2002). Randomised Controlled Trials Investigating Pharmacological and Psychological Interventions for Treatment-Refractory Depression. Systematic Review. British Journal of Psychiatry, 181, 284.
[CrossRef] [PubMed]
[31] Swanson, J. M. (2012). The UK Biobank and Selection Bias. The Lancet, 380, 110.
[32] Whelan, R., Watts, R., Orr, C. A., Althoff, R. R., Artiges, E., Banaschewski, T., Barker, G. J., Bokde, A. L. W., Büchel, C., & Carvalho, F. M. (2014). Neuropsychosocial Profiles of Current and Future Adolescent Alcohol Misusers. Nature, 512, 185.
[CrossRef] [PubMed]
[33] Williams, L. M., Korgaonkar, M. S., Song, Y. C., Paton, R., Eagles, S., Goldsteinpiekarski, A. N., Grieve, S. M., Harris, A., Usherwood, T., & Etkin, A. (2015). Amygdala Reactivity to Emotional Faces in the Prediction of General and Medication-Specific Responses to Antidepressant Treatment in the Randomized iSPOT-D Trial. Neuropsychopharmacology, 40, 2398-2408.
[CrossRef] [PubMed]
[34] Woo, C. W., Chang, L. J., Lindquist, M. A., & Wager, T. D. (2017). Building Better Biomarkers: Brain Models in Translational Neuroimaging. Nature Neuroscience, 20, 365-377.
[CrossRef] [PubMed]
[35] Yarkoni, T., & Westfall, J. (2017). Choosing Prediction over Explanation in Psychology: Lessons from Machine Learning. Perspectives on Psychological Science: A Journal of the Association for Psychological Science, 12, 1745691617693393.
[36] Young, K. D., Drevets, W. C., Bodurka, J., & Preskorn, S. S. (2016). Amygdala Activity during Autobiographical Memory Recall as a Biomarker for Residual Symptoms in Patients Remitted from Depression. Psychiatry Research, 248, 159-161.
[CrossRef] [PubMed]