夏侧金盏花中化学成分的分离鉴定及活性研究
Isolation, Identification and Bioacitivity Study of Chemical Components in Adonis aestivalis L.
摘要: 夏侧金盏花(Adonis aestivalis L.)是一种毛茛目，毛茛科的一年生草本植物，利用有机溶剂进行提取得到粗提物，所得粗提物用正相硅胶、反相硅胶、SephadexLH-20凝胶与制备薄层色谱(pTLC)等进行分离得到7个单体化合物，通过核磁共振波谱、质谱等鉴定得出化合物的结构，其中化合物1、2、3、4都是黄酮类化合物，化合物5、6、7为甾体类化合物，对所得到的化合物进行相关性质测试，并对所得到的化合物进行了DPPH活性测试，黄酮类化合物的抗氧化活性较强，为夏侧金盏花的种植使用提供了科学的依据。
Abstract:
Adonis aestivalis L. is a kind of annual herb of the genus Ranunculaceae. The crude extract was ex-tracted with organic solvent and 7 compounds were obtained from it. These compounds were iso-lated by a combination of usage of silica gel, Sephadex LH-20 and preparative of thin layer chro-matography (pTLC). The structures of the compounds were identified by nuclear magnetic reso-nance spectroscopy, mass spectrometry, etc. Compounds 1, 2, 3, and 4 were all flavonoids, and compounds 5, 6 and 7 were steroids. The compounds were tested; DPPH activity and the activity of the flavonoid analogues were potent, which provided a scientific basis for the planting of the summer marigold flower.
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