信必可都保联合呼吸训练对慢性阻塞性肺疾病稳定期的患者肺功能及血气分析的疗效探讨

Therapeutic Effect of Symbicort Turbuhaler Combined with Respiratory Training on Pulmonary Function and Blood Gas Analysis in Patients with Stable Chronic Obstructive Pulmonary Disease

摘要: 目的：探讨信必可都保联合呼吸训练对慢性阻塞性肺疾病稳定期患者肺功能和血气指标的改善效果。方法：选择本院2016年4月~2018年5月收治的稳定期慢性阻塞性肺疾病(chronic obstructive pulmonary disease, COPD)患者126例，以双盲法分为参照组和治疗组各63例，两组均采取常规综合治疗，参照组在此基础上采取信必可都保(布地奈德福莫特罗)治疗，治疗组采取信必可都保联合呼吸训练。观察对比两组患者肺功能和血气指标。结果：6个月后治疗组FEV1、PEF、FEV1/FVC、PaO2、SaO2均高于参照组，且PaCO2低于参照组，P < 0.05。结论：信必可都保联合呼吸训练可有效改善COPD稳定期患者肺功能和血气指标，有临床应用价值。

Abstract: Objective: To investigate the effect of symbicort turbuhaler combined with respiratory training on lung function and blood gas index in patients with stable chronic obstructive pulmonary disease. Methods: A total of 126 patients with stable chronic obstructive pulmonary disease (COPD) ad-mitted to our hospital from April 2016 to May 2018 were enrolled. The patients were divided into a reference group and a treatment group by 63 cases. For the combined treatment, the reference group was treated with symbicort turbuhaler on the basis of this, and the treatment group was treated with symbicort turbuhaler combined with respiratory training. The lung function and blood gas index of the two groups were observed and compared. Results: After 6 months, FEV1, PEF, FEV1/FVC, PaO2, and SaO2 in the treatment group were higher than the reference group, and PaCO2 was lower than the reference group, P < 0.05. Conclusion: Symbicort turbuhaler combined with respiratory training can effectively improve lung function and blood gas index in patients with stable COPD, and has clinical application value.