应用等体温冲洗液在前交通动脉瘤夹闭术中对脑血流量影响的探讨研究

Study on the Effect of Isothermic Flushing Solution on Cerebral Blood Flow during Anterior Communicating AneurysmClipping

摘要: 目的：研究等体温冲洗液在前交通动脉瘤夹闭术中对患者脑血流量产生的影响。方法：本研究于2015年7月~2017年7月选取了院内收治的240例拟行前交通动脉瘤开颅夹闭术患者作为研究对象，随机将其分为研究组和对照组各120例，对比两组患者不同时间段的脑血流量、鼻咽温度以及术后并发症发生率。结果：两组患者T1时间的脑血流量指标相比无统计学意义(P > 0.05)，研究组和对照组患者T2和T3时间的脑血流量均明显优于T1时间，且研究组的T2和T3脑血流量均优于对照组T2和T3的脑血流量(P < 0.05)；两组患者T1时间的鼻咽温度相比无统计学意义(P > 0.05)，研究组T2和T3时间的鼻咽温度均明显高于对照组的T2和T3时间(P < 0.05)，对照组T2和T3时间的鼻咽温度明显低于T1时间(P < 0.05)；研究组的术后并发症发生率略低于对照组，但无统计学意义(P > 0.05)。结论：等体温冲洗液可以增加前交通动脉瘤患者术中的脑血流量速度，且有利于降低患者的术后并发症发生率，宜广泛应用和推广。

Abstract: Objective: To study the effect of body temperature rinse solution on cerebral blood flow in patients with anterior communicating artery aneurysm. Methods: From July 2015 to July 2017, 240 patients with craniotomy before delivery were selected as the study subjects. The patients were randomly divided into study group and control group (120 cases). Cerebral blood flow, nasopharyngeal tem-perature and postoperative complications at different time of the two groups were compared. Re-sults: There was no significant difference in cerebral blood flow rate at T1 between the two groups (P > 0.05). However, in T2 and T3 time, the cerebral blood flow rate between the two groups was significantly better than the T1 time; and the cerebral blood flow in the study group was better than that of the control group T2 and T3 time (P < 0.05). There was no significant difference in nasopharyngeal temperature between the two groups at T1 time (P > 0.05); however, in T2 and T3 time, the nasopharyngeal temperature of study group was significantly higher than the control group; and nasopharyngeal temperature in the study group at T2 and T3 time was lower than that of TI time (P < 0.05); the incidence of postoperative complications was slightly lower in the study group than in the control group, but it was not statistically significant (P > 0.05). Conclusion: Body temperature rinse solution can effectively reduce the rate of cerebral blood flow in patients with anterior communicating artery aneurysm, and it is helpful to reduce the incidence of postoperative complications. It should be widely used and popularized.