预见性护理对妊娠期肝内胆汁淤积症临床效果、妊娠结局及TBIL水平的影响
The Effect of Predictive Nursing on theClinical Effect of Intrahepatic Cholestasisof Pregnancy, the Outcome of Pregnancyand the Level of TBIL
摘要: 目的:分析妊娠期肝内胆汁淤积症应用预见性护理的效果及对妊娠结局、TBIL水平的影响。方法:选择我院2016年2月~2018年2月诊治的72例妊娠期肝内胆汁淤积症患者,随机分成研究组(36例)和对照组(36例)。对照组接受常规护理,研究组进行预见性护理,比较两组护理效果。结果:研究组护理后TBIL (13.74 ± 3.26) μmol/L、TBA (10.25 ± 2.43) μmol/L、AST (54.32 ± 11.74) U/L、ALT (40.56 ± 8.67) U/L优于对照组的(17.37 ± 5.70) μmol/L、(49.47 ± 10.81) U/L、(13.58 ± 3.78) μmol/L和(71.84 ± 11.97) U/L,比较差异具有统计学意义(P < 0.05);研究组SDS (37.56 ± 8.73)分、SAS (36.81 ± 7.23)分,低于对照组,比较差异具有统计学意义(P < 0.05);研究组早产8.33%、胎儿宫内窘迫2.78%、剖宫产30.56%等妊娠结局均优于对照组,比较差异具有统计学意义(P < 0.05);研究组满意度97.22%高于对照组的77.78%,比较差异具有统计学意义(P < 0.05)。结论:预见性护理在妊娠期肝内胆汁淤积症护理中的应用效果显著,可明显降低TBIL水平,改善患者的心理状态,改善妊娠结局,且患者满意度高。
Abstract: Objective: To analyze the effect of predictive nursing on intrahepatic cholestasis of pregnancy and its effect on the outcome of pregnancy and TBIL. Methods: 72 patients with intrahepatic cholestasis of pregnancy were randomly divided into the research group (36 cases) and the control group (36 cases). The control group received routine nursing, and the study group performed the predictive nursing; nursing effects of the two groups were compared. Results: TBIL (13.74~3.26) μmol/L, TBA (10.25~2.43) μmol/L, AST (54.32 ± 11.74) U/L, ALT (40.56 ± 8.67) U/L of the study group after nursing were better than those of the control group [(17.37 ± 5.70) μmol/L, (49.47 ± 10.81) U/L, (13.58 ± 3.78) μmol/L and (71.84 ± 11.97) U/L, respectively]. The difference was statistically significant (P < 0.05). In the study group, the SDS score was (37.56 ± 8.73), and the SAS score was (36.81 ± 7.23) which were significantly lower than those in the control group; there was a significant difference between the two groups (P < 0.05). Premature birth accounted for 33%, fetal distress 2.78%, and cesarean section 30.56% of the research group, which were all better than those of control group (P < 0.05). The satisfaction rate of the study group was 97.22%, which was significantly higher than that of the control group (77.78%), having a statistically significant difference (P < 0.05). Conclusion: Predictive nursing is effective in the nursing of intrahepatic cholestasis of pregnancy. It can obviously reduce the level of TBIL, improve the mental state of the patients, and improve the outcome of pregnancy, and the satisfaction of the patients is high.
文章引用:陈雅芬, 沈红卫. 预见性护理对妊娠期肝内胆汁淤积症临床效果、妊娠结局及TBIL水平的影响[J]. 护理学, 2019, 8(2): 99-104. https://doi.org/10.12677/NS.2019.82020

参考文献

[1] 丁霄雁, 耿慧, 段彼得. 乙型肝炎病毒感染对孕妇妊娠期肝内胆汁淤积症的影响研究[J]. 中华医院感染学杂志, 2015, 25(2): 433-435.
[2] 李杰. 自拟利胆退黄汤治疗妊娠肝内胆汁淤积症临床疗效观察[J]. 中华中医药学刊, 2015, 33(11): 2807-2811.
[3] 朱军梅, 陆亚康. 熊去氧胆酸结合清瘀利胆汤治疗妊娠期肝内胆汁淤积症的临床观察[J]. 中华中医药学刊, 2014, 32(03): 677-680.
[4] 葛星, 徐叶清, 黄三唤, 等. 妊娠期肝内胆汁淤积症对分娩结局影响的出生队列研究[J]. 中华流行病学杂志, 2016, 37(2): 187-191.
[5] Gabzdyl, E.M. and Schiaeger, J.M. (2015) Intrahepatic Cholestasis of Pregnancy: A Critical Clinical Review. Journal of Perinateal &Neonatal Nursing, 29, 41-50. [Google Scholar] [CrossRef
[6] 张雅琴, 沈玲珑. 餐后2小时血清甘胆酸测定对妊娠期肝内胆汁淤积症的早期诊断意义[J]. 中华全科医学, 2015, 13(4): 636-637.
[7] 孙彩萍, 张珂, 王倩, 等. 妊娠期肝内胆汁淤积症发病危险因素及其对妊娠结局的影响分析[J]. 中华全科医学, 2017, 15(7): 1130-1132.
[8] 徐晖, 黄夏冰, 伍涛. 妊娠期肝内胆汁淤积症患者相关生化指标的检测及临床意义[J]. 中华全科医学, 2017, 15(7): 1192-1193+1197.
[9] 魏琴, 徐志红, 覃光兰, 等. 熊去氧胆酸联合S-腺苷蛋氨酸治疗妊娠期肝内胆汁淤积症的价值研究[J]. 中华全科医学, 2016, 14(4): 607-608+675.
[10] Diken, Z., Uata, I.M. and Nassar, A.H. (2014) A Clinical Ap-proach to Intra-Hepatic Cholestasis of Pregnancy. American Journal of Perinatology, 31, 1.
[11] 任思佳, 殷艳, 王冬梅. 妊娠期肝内胆汁淤积症患者不同生化指标临床意义比较[J]. 中华实用诊断与治疗杂志, 2011, 25(6): 596-597.
[12] 孙录仙. 妊娠期肝内胆汁淤积症120例分析[J]. 中华全科医学, 2011, 9(6): 885-886.
[13] 张盛燕, 金丽桂, 陈青娇. 乙型肝炎病毒感染对妊娠期肝内胆汁淤积症妊娠结局影响研究[J]. 中华医院感染学杂志, 2011, 21(22): 4725-4726.
[14] 杨德, 陈素华. 腺苷蛋氨酸治疗妊娠期肝内胆汁淤积症36例临床分析[J]. 中华实用诊断与治疗杂志, 2009, 23(10): 1017-1018.
[15] Geenes, V., Chappell, L.C., Seed, P.T., et al. (2014) Association of Severe Intrahepatic Cholestasis of Pregnancy with Adverse Pregnancy Outcomes: A Prospective Population-Based Case Control Study. Hepatology, 59, 1482 -1491. [Google Scholar] [CrossRef] [PubMed]
[16] 马文芳, 王伟. 86例妊娠期肝内胆汁淤积症临床分析及护理[J]. 中华护理杂志, 2007(6): 525-526.
[17] 褚红女, 陈红娟. 低分子肝素治疗妊娠期肝内胆汁淤积症的护理要点[J]. 中华护理杂志, 2003(12): 20-21.
[18] 漆洪波, 邵勇, 吴味辛, 张建华. 妊娠肝内胆汁淤积症分度诊断和处理的临床意义[J]. 中华妇产科杂志, 2004(1): 17-20.