Survivin基因的研究进展
Advances on the Study of Survivin Gene
DOI: 10.12677/AMS.2019.62005, PDF,    国家科技经费支持
作者: 李 炎*:中国海洋大学,海洋生命学院,海洋生物遗传学与育种教育部重点实验室,山东 青岛;郭华荣*:中国海洋大学,海洋生命学院,海洋生物遗传学与育种教育部重点实验室,山东 青岛;中国海洋大学,海洋生物多样性与进化研究所,山东 青岛
关键词: SurvivinBIR细胞凋亡Survivin BIR Cell Apoptosis
摘要: Survivin基因是凋亡抑制蛋白(Inhibitor of apoptosis protein, IAP)家族成员之一,具有一个典型的杆状病毒重复序列(Baculovirus inhibitior of apoptosis protein repeat, BIR)。Survivin在控制细胞周期和抑制细胞凋亡方面具有十分重要的作用。本文对Survivin基因结构、生物学功能以及在不同物种中的研究进展进行了综述,并对其在海洋无脊椎动物中的应用进行了展望。
Abstract: Survivin is a member of inhibitor of apoptosis protein family and has a typical baculovirus inhibitior of apoptosis protein repeat, BIR domain. Survivin plays an important role in controlling cell cycle and inhibiting apoptosis. In this review, we briefly summarized the structure, biological function and research progress of Survivin gene in different species, and the application in marine invertebrates is also prospected.
文章引用:李炎, 郭华荣. Survivin基因的研究进展[J]. 海洋科学前沿, 2019, 6(2): 41-45. https://doi.org/10.12677/AMS.2019.62005

参考文献

[1] Li, F., Ambrosini, G., Chu, E.Y., Plescia, J., Tognin, S., Marchisio, P.C. and Altieri, D.C. (1998) Control of Apoptosis and Mitotic Spindle Checkpoint by Survivin. Nature, 396, 580-584. [Google Scholar] [CrossRef] [PubMed]
[2] Kerr, J.F.R., Wyllie, A.H. and Currie, A.R. (1972) Apoptosis: A Basic Biological Phenomenon with Wide-Ranging Implications in Tissue Kinetics. British Journal of Cancer, 26, 239-257. [Google Scholar] [CrossRef] [PubMed]
[3] Crook, N.E., Clem, R.J. and Miller, L.K. (1993) An Apoptosis-Inhibiting Baculovirus Gene with a Zinc Finger-Like Motif. Journal of Virology, 67, 2168-2174.
[4] Ambrosini, G., Adida, C. and Altieri, D.C. (1997) A Novel Anti-Apoptosis Gene, Survivin, Expressed in Cancer and Lymphoma. Nature Medicine, 3, 917-921. [Google Scholar] [CrossRef] [PubMed]
[5] 王志成, 郭德玉. Survivin与肿瘤[J]. 重庆医学, 2005, 34(1): 130-132.
[6] Tamm, I., Wang, Y.E., Scudiero, D., Vigna, N., Oltersdorf, T. and Reed, J.C. (1998) IAP-Family Protein Survivin Inhibits Caspase Activity and Apoptosis Induced by Fas (CD95), Bax, Caspases, and Anticancer Drugs. Cancer Research, 58, 5315-5320.
[7] Jaiswal, P.K., Goel, A. and Mittal, R.D. (2015) Survivin: A Molecular Biomarker in Cancer. The Indian Journal of Medical Research, 141, 389-397. [Google Scholar] [CrossRef] [PubMed]
[8] Suzuki, A., Ito, T., Kawano, H., Hayashida, M., Hayasaki, Y., Tsutomi, Y., Nakano, T., Miura, M. and Shiraki, K. (2000) Survivin Initiates Procaspase 3/p21 Complex Formation as a Result of Interaction with Cdk4 to Resist Fas-Mediated Cell Death. Oncogene, 19, 1346-1353. [Google Scholar] [CrossRef] [PubMed]
[9] Zhao, J., Tenev, T., Martins, L.M., Downward, J. and Lemoine, N.R. (2001) The Ubiquitin-Proteasome Pathway Regulates Survivin Degradation in a Cell Cycle-Dependent Manner. Journal of Cell Science, 113, 4363-4371.
[10] Schechner, J.S., Adida, C., Mesri, M., Rothermei, A.L., Nath, A.K., Pober, J.S., Altieri, D.C., et al. (2000) Control of Apoptosis during Angiogenesis by Survivin Expression in Endothelial Cells. American Journal of Pathology, 156, 393-398. [Google Scholar] [CrossRef
[11] Kanwar, J.R., Kamalapuram, S.K. and Kanwar, R.K. (2013) Survivin Signaling in Clinical Oncology: A Multifaceted Dragon. Medicinal Research Reviews, 33, 765-789. [Google Scholar] [CrossRef] [PubMed]
[12] Peery, R.C., Liu, J.Y. and Zhang, J.T. (2017) Targeting Survivin for Therapeutic Discovery: Past, Present, and Future Promises. Drug Discovery Today, 22, 1466-1477. [Google Scholar] [CrossRef] [PubMed]
[13] Mesri, M., Wall, N.R., Li, J., Kim, R.W. and Altieri, D.C. (2001) Cancer Gene Therapy Using Survivin Mutant Adenovirus. Journal of Clinical Investigation, 108, 981-990. [Google Scholar] [CrossRef
[14] 潘黎, 彭星辰, 袁庆中, 冷斐, 于丹丹, 单艳, 李志勇, 王春婷. Survivin突变基因抗前列腺癌的体内外研究[J]. 四川大学学报(医学版), 2010, 41(3): 390-393.
[15] Kar, R., Palanichamy, J., Banerjee, A., Chat-topadhyay, P., Jan, S.K. and Singh, N. (2015) Survivin siRNA Increases Sensitivity of Primary Cultures of Ovarian Cancer Cells to Paclitaxel. Clinical & Translational Oncology, 17, 737-742. [Google Scholar] [CrossRef] [PubMed]
[16] 李秀梅, 陈艳, 姜孝芳, 李卉, 郭琼, 李惠武, 谌宏鸣. 食管癌ECA109细胞中Survivin shRNA干扰对核因子κB表达的影响及调控机制[J]. 解剖学报, 2015, 46(4): 514-520.
[17] Pasquier, D.D., Phung, A.C., Ymlahi-Ouazzani, Q., Sinzelle, L., Ballagny, C., Brochain, O., Pasquier, L.D. and Mazabraud, A. (2006) Survivin Increased Vascular Development during Xenopus ontogenesis. Differentiation, 74, 244-253. [Google Scholar] [CrossRef] [PubMed]
[18] Delvaeye, M., Vriese, A.D., Zwerts, F., Belz, I., Moons, M., Autiero, M. and Conway, E.M. (2009) Role of the 2 Zebrafish Survivin Genes in Vasculo-Angiogenesis, Neurogenesis, Cardiogenesis and He-matopoiesis. BMC Developmental Biology, 9, 25. [Google Scholar] [CrossRef
[19] Ma, A., Lin, R., Chan, P., Leung, J.C., Chan, L.Y., Meng, A., Verfaillie, C.M., Liang, R. and Leung, A.Y. (2007) The Role of Survivin in Angiogenesis during Zebrafish Embryonic Development. BMC Developmental Biology, 7, 50. [Google Scholar] [CrossRef
[20] Uren, A.G., Beilharz, T., O’Connell, M.J., Bugg, S.J., Driel, R., Vaux, D.L. and Lithgow, T. (1999) Role for Yeast Inhibitor of Apoptosis (IAP)-Like Proteins in Cell Division. Proceedings of the National Academy of Sciences, 96, 10170-10175. [Google Scholar] [CrossRef] [PubMed]
[21] Jones, G., Jones, D., Zhou, L., Steller, H. and Chu, Y. (2000) Deterin, a New Inhibitor of Apoptosis from Drosophila melanogaster. Journal of Biological Chemistry, 275, 22157-22165. [Google Scholar] [CrossRef
[22] Leu, J.H., Kuo, Y.C., Kou, G.H. and Lo, C.F. (2008) Molecular Cloning and Characterization of an Inhibitor of Apoptosis Protein (IAP) from the Tiger Shrimp, Penaeus monodon. Developmental and Compar-ative Immunology, 32, 121-133. [Google Scholar] [CrossRef] [PubMed]
[23] Leu, J.H., Chen, Y.C., Chen, L.L., Chen, K.Y., Huang, H.T., Ho, J.M. and Lo, C.F. (2012) Litopenaeus vannamei Inhibitor of Apoptosis Protein 1 (LvIAP1) Is Essential for Shrimp Survival. Developmental and Comparative Immunology, 38, 78-87. [Google Scholar] [CrossRef] [PubMed]
[24] Wang, P.H., Wan, D.H. and Gu, Z.H. (2013) Analysis of Expression, Cellular Localization, and Function of Three Inhibitors of Apoptosis (IAPs) from Litopenaeus vannamei during WSSV Infection and in Regulation of Antimicrobial Peptide Genes (AMPs). PLoS ONE, 8, e72592. [Google Scholar] [CrossRef] [PubMed]