以癫痫持续状态为首发症状的急性髓系白血病1例报告并文献复习
A Case of Acute Myeloid Leukemia with Initial Symptoms of Generalized Tonic Clonic Seizure and Related Literature Review
摘要:
目的:报道以癫痫持续状态为首发症状的急性髓系白血病1例,分析其临床特征和发病机制,提高神经科医生对该疾病的认识。方法:对1例以癫痫持续状态为首发症状的急性髓系白血病患者的临床资料,结合文献进行回顾性分析。结果:以癫痫持续状态为首发症状的急性髓系白血病发病机制复杂,病程凶险,进展更快。结论:以癫痫持续状态为首发症状的急性髓系白血病少见,易误诊、漏诊,早期诊断、早期治疗对患者的预后十分重要。
Abstract:
Aim: To report 1 case of acute
myeloid leukemia (AML) with initial symptoms of Generalized Tonic Clonic
Seizure (GTCS), and analyze its clinical characteristics and pathogenesis.
Methods: The clinical data of the patient with acute myeloid leukemia, who
displayed initial symptoms of GTCS, combined with literature were retrospectively
analyzed. Results: It is rare for the patient with acute myeloid leukemia
displaying initial symptoms of GTCS. When combined with diffuse intravascular
coagulation, the situation would be dangerous and progress rapidly. Conclusion:
The GTCS as starting symptoms of acute myeloid leukemia is rare, which is
easily misdiagnosed and missed diagnosis; early diagnosis and early treatment
is very important for the prognosis of the patients.
参考文献
|
[1]
|
Li, Y., Suo, S., Mao, L., et al. (2015) Acute Myocardial Cerebral Infarction as First Relapse Manifestation in One Acute Promyelocytic Leukemia Patient. International Journal of Clinical and Experimental Medicine, 8, 14210-14213.
|
|
[2]
|
Kapoor, R., Pati, H.P., Gupta, S.K., et al. (2013) Acute Promyelocytic Leukemia Presenting as Is-chemic Stroke in Young. Indian Journal of Hematology and Blood Transfusion, 29, 93-95. [Google Scholar] [CrossRef] [PubMed]
|
|
[3]
|
Fraint, E., Miller, R. and Waler, A. (2017) Posterior Reversible Encephalopathy Syndrome and Cerebral Sinus Thrombosis in a Case of Pediatric B-Cell All. Journal of Pediatric He-matology Oncology, 39, e71-e73. [Google Scholar] [CrossRef]
|
|
[4]
|
Ma, G., Liu, F., Lv, L., et al. (2013) Increased Promyelocytic-Derived Microparticles: A Novel Potential Factor for Coagulopathy in Acute Promyelocytic Leukemia. Annals of Hematology, 92, 645-652. [Google Scholar] [CrossRef] [PubMed]
|
|
[5]
|
Kishore, M., Kumar, V., et al. (2016) Unusual Presentation of Acute Leukemia: A Tripod of Cases. Journal of Clinical and Diagnostic Research, 10, ED04-ED08. [Google Scholar] [CrossRef]
|
|
[6]
|
Yesilot, B.N., Putaala, J., et al. (2013) Etiology of First-Ever Ischemic Stroke in European Young Adults: The 15 Cities Young Stroke Study. European Journal of Neurology, 20, 1431-1439.
|
|
[7]
|
耿丛, 张颖冬, 赵红东. 急性早幼粒细胞白血病所致脑梗死1例报道并文献复习[J]. 卒中与神经疾病, 2015, 22(5): 295-298.
|