视网膜小胶质细胞关于青光眼诱导的视神经损伤的研究进展
Glaucoma-Induced Optic Nerve Injury on Retinal Microglia
DOI: 10.12677/HJO.2020.91003, PDF,    国家自然科学基金支持
作者: 孙凯迪, 王佳琪:内蒙古民族大学,内蒙古 通辽;张秋丽:内蒙古民族大学,内蒙古 通辽;广东医科大学附属医院眼科,广东 湛江
关键词: 视网膜小胶质细胞青光眼视神经损伤Retinal Microglia Glaucoma The Optic Nerve
摘要: 随着对青光眼性视功能丧失认识的不断深入,发现青光眼是一种以高眼压、疼痛和视网膜神经节细胞变性为特征的复杂疾病,它会造成不可逆转的视力损害和失明。尽管多种原因与青光眼视网膜神经节细胞损伤有关,但视网膜小胶质细胞因其作为中枢神经系统中最有代表性的免疫细胞而成为青光眼发病机制的研究热点之一。因此,我们就视网膜小胶质细胞及青光眼视神经损伤之间的相互作用关系进行综述。
Abstract: With the further study of the visual loss caused by glaucoma, glaucoma has been found to be a complex disease characterized by intraocular hypertension, pain and degeneration of retinal ganglion cells, which can give rise to irreversible visual impairment and blindness. Although there are many reasons related to the damage of retinal ganglion cells caused by glaucoma, ret-inal microglia, being the most representative immune cells in the central nervous system, has become one of the research hotpots on the pathogenesis of glaucoma. Therefore, the interaction between retinal microglia and glaucomatous optic nerve damage will be discussed in this thesis.
文章引用:孙凯迪, 王佳琪, 张秋丽. 视网膜小胶质细胞关于青光眼诱导的视神经损伤的研究进展[J]. 眼科学, 2020, 9(1): 16-20. https://doi.org/10.12677/HJO.2020.91003

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