浓缩生长因子应用于下颌前牙区牙龈瘤切除术后角化龈修复1例

Application of CGF in Keratinized Gingiva Repair after Epulis Resection

摘要: 目的：总结牙龈瘤的临床特点，为牙龈瘤术后角化龈缺损修复提供新的治疗方法。方法：选择临床上下颌前牙区牙龈瘤患者1例，术前进行系统牙周治疗后行牙龈瘤切除术，术后使用浓缩生长因子(Concentrated growth factor, CGF)覆盖术区角化龈缺损创面，观察角化龈的修复水平。结果：CGF覆盖术区创面后，患者未述明显的术后疼痛、肿胀等反应；术后1个月及6个月复查时可见一定程度的角化龈组织再生，效果满意。结论：CGF作为一种临床制备较易的生物材料，能够在牙龈瘤术后覆盖角化龈缺损创面，缓解术后疼痛，同时CGF覆盖创面能够促进角化龈再生，是一种较好的修复角化龈缺损的治疗方法。

Abstract: Epulis is the neoplastic lesion of gingiva derived from the periodontal ligament and/or the alveolar connective tissues. Surgical resection is the primary treatment of epulis. Epulis is frequently involved in the gingival papilla and surgery usually causes local keratinized gingiva loss, resulting in the anesthetic defect and tissue dysfunction. Clinical experiments have indicated the positive roles of concentrated growth factor (CGF) in promoting the healing of soft and hard tissues. The paper presents a case of keratinized gingiva repair after epulis resection by use of CGF, which pro-vides a new method for gingiva repair.