早期原发性肝脏肉瘤样癌1例报告
Case Report of Primary Liver Sarcomatous Carcinoma at Early-Stage
DOI: 10.12677/ACM.2020.103045, PDF,   
作者: 鲍 利, 黄佳程, 陈芝涛, 万大龙, 林胜璋:浙江大学医学院附属第一医院肝胆胰外科,浙江 杭州
关键词: 肉瘤样癌肝脏乙型肝炎病毒预后Sarcomatous Carcinoma Liver Hepatitis B Virus Prognosis
摘要: 肝脏肉瘤样癌临床上少见,目前病因不明,可能与乙型肝炎病毒感染和术前抗癌治疗有关。患者临床表现和影像学表现缺乏特征性,术前诊断此病比较困难,确诊依赖病理学和免疫组织化学检查。肝脏肉瘤样癌预后差,缺乏有效的治疗方法,目前手术仍是有望延长患者生存时间的治疗方法。本研究报道了1例预后相对较好的早期原发性肝脏肉瘤样癌。
Abstract: Liver sarcomatous carcinoma is a rare malignant tumor. The pathogenesis remains unknown, hepatitis B virus infection and anti-cancer therapy may be the potential cause of this disease. The atypical clinical symptom and image feature of this disease make it difficult to be accurately diag-nosed without pathology and immunohistology. Liver sarcomatous carcinoma has a poor prognosis and lacks effective treatments. At present, surgery is still a treatment that is expected to extend the survival time of patients. This study reported a rare case of primary liver sarcomatous carcinoma at early-stage with relatively better prognosis.
文章引用:鲍利, 黄佳程, 陈芝涛, 万大龙, 林胜璋. 早期原发性肝脏肉瘤样癌1例报告[J]. 临床医学进展, 2020, 10(3): 284-288. https://doi.org/10.12677/ACM.2020.103045

参考文献

[1] 纪小龙, 刘爱军. 癌肉瘤的现代概念及常见部位“癌肉瘤”的病理诊断[J]. 诊断病理学杂志, 1995(1): 47-48.
[2] Lu, J., Zhang, J., Xiong, X., Li, F., Ye, H., Cheng, Y., et al. (2014) Primary Hepatic Sarcomatoid Carci-noma: Clinical Features and Prognosis of 28 Resected Cases. Journal of Cancer Research and Clinical Oncology, 140, 1027-1035. [Google Scholar] [CrossRef] [PubMed]
[3] Wang, Q., Cui, B., Weng, J., Wu, Q., Qiu, J. and Lin, X. (2012) Clinicopathological Characteristics and Outcome of Primary Sarcomatoid Carcinoma and Carcinosarcoma of the Liver. Journal of Gastrointestinal Surger, 16, 1715-1726. [Google Scholar] [CrossRef] [PubMed]
[4] Kojiro, M., Sugihara, S., Kakizoe, S., Nakashima, O. and Kiyomatsu, K. (1989) Hepatocellular Carcinoma with Sarcomatous Change: A Special Reference to the Relationship with Anticancer Therapy. Cancer Chemotherapy and Pharmacology, 23. [Google Scholar] [CrossRef
[5] 尚培中, 李永庆, 李兴杰. 肝肉瘤样癌的诊断与治疗[J]. 中华普通外科学文献, 2016, 10(5): 378-380.
[6] Li, Z., Huang, Z., Bi, X., Yang, L., Zhao, J., Zhao, H., et al. (2014) Clinical Characteristics and Prognosis of Three Rare and Poor-Prognostic Subtypes of Primary Liver Carcinoma. Chinese Journal of Oncology, 36, 207-211.
[7] W N, M I, T K, T K. (2003) Sarcomatoid Carcinoma of the Liver with Skin and Pleural Metastases. British Journal of Dermatology 148, 1069-1071. [Google Scholar] [CrossRef] [PubMed]
[8] 阮小蛟, 暨玲, 朱恒梁, 郑晓风, 蒋飞照. 原发性肝脏肉瘤样癌临床特征及外科治疗[J]. 温州医科大学学报, 2014, 44(10): 752-755.
[9] Shi, D., Ma, L., Zhao, D., Chang, J., Shao, C., Qi, S., et al. (2018) Imaging and Clinical Features of Primary Hepatic Sarcomatous Carcinoma. CANCER IMAGING, 18. [Google Scholar] [CrossRef] [PubMed]
[10] Giunchi, F., Vasuri, F., Baldin, P., Rosini, F., Corti, B.D. and Errico-Grigioni, A. (2013) Primary Liver Sarcomatous Carcinoma: Report of Two Cases and Review of the Literature. Pathology-Research and Practice, 209, 249-254. [Google Scholar] [CrossRef] [PubMed]
[11] 黄海建, 余英豪, 郑智勇. 肝肉瘤样癌的临床病理特征[J]. 世界华人消化杂志, 2010, 18(17): 1780-1785.
[12] Liao, S., Su, T., Jeng, Y., Liang, P., Chen, D., Chen, C., et al. (2019) Clinical Manifestations and Outcomes of Patients with Sarcomatoid Hepatocellular Carcinoma. Hepatology, 69, 209-221. [Google Scholar] [CrossRef] [PubMed]
[13] Wu, L., Tsilimigras, D.I., Farooq, A., Hyer, J.M., Merath, K., Paredes, A.Z., et al. (2019) Management and Outcomes among Patients with Sarcomatoid Hepatocellular Carcinoma: A Population-Based Analysis. Cancer, 125, 3767-3775. [Google Scholar] [CrossRef] [PubMed]