细胞免疫与1型糖尿病的研究进展
Research Progress of Cellular Immunity and Type 1 Diabetes Mellitus
DOI: 10.12677/HJBM.2020.102002, PDF,   
作者: 牟 畅, 吴 亮：中国药科大学，江苏 南京
关键词: 1型糖尿病；细胞免疫；淋巴细胞；Type 1 Diabetes； Cellular Immunity； Lymphocytes
摘要: 1型糖尿病(Type 1 diabetes mellitus, T1DM)是一种具有致病性、适应性和自身免疫性的复杂疾病，可导致β细胞的破坏和功能障碍。目前，普遍认为T细胞是大多数T1DM患者β细胞损伤的关键介质，此外，B细胞、巨噬细胞及树突状细胞等也在其发病过程中发挥着不容忽视的作用。
Abstract: Type 1 diabetes mellitus (T1DM) is a complex disease that is pathogenic, adaptive, and autoim-mune, which can cause β-cell destruction and dysfunction. At present, T cells are generally con-sidered to be the key mediator of β cell damage in most T1DM patients. In addition, B cells, mac-rophages, and dendritic cells also play a role that cannot be ignored.
文章引用：牟畅, 吴亮. 细胞免疫与1型糖尿病的研究进展[J]. 生物医学, 2020, 10(2): 9-12. https://doi.org/10.12677/HJBM.2020.102002

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