潜伏期具有传染性的水痘模型的分析
Analysis of a Varicella Model Incorporating Infectious Force in Latent Period
摘要: 研究了一类潜伏期具有传染性的水痘模型,并考虑复发,隔离以及接种疫苗的因素。得到了水痘模型的基本再生数,利用李雅普诺夫第二方法证明水痘模型的全局动力学性态完全由基本再生数所控制。即当基本再生数小于1时,水痘病毒会在人群中逐渐消失;当基本再生数大于1时,水痘病毒不会绝灭并且在人群中形成地方病。
Abstract:
A varicella model with infectious force during the latent period has been considered with the factors of relapse, quarantine and vaccination taken into account. The basic reproduction number of the varicella model is obtained, and the varicella model’s global dynamics are completely controlled by the basic reproduction number by using the second method of Lyapunov. If the basic reproduction number is under one, the varicella virus gradually disappears in the population; while if the basic reproduction number is above one, the varicella virus does not eradicate and becomes an endemic disease in the population.
参考文献
|
[1]
|
郭宁燕. 水痘防控. 临床和实验医学杂志[J]. 2010(96): 468-469.
|
|
[2]
|
丁信宏. 传染病动力学模型在水痘疫情预测和防控措施效果评价中的应用研究[J]. 医药前沿, 2014(30): 17-18.
|
|
[3]
|
邓旋, 何寒青, 周洋, 等. 水痘疫苗不同免疫策略的卫生经济学评价[J]. 浙江大学学报(医药版), 2018, 47(4): 374-380.
|
|
[4]
|
潘金仁. 传染病动力学模型在水痘疫情预测和防控措施效果评价中的应用[D]: [硕士学位论文]. 杭州: 浙江大学, 2011.
|
|
[5]
|
Ziv, E., Daley, C.L. and Blower, S.M. (2001) Early Therapy for Latent Tuberculosis Infection. American Journal of Epidemiology, 153, 381-385. [Google Scholar] [CrossRef] [PubMed]
|
|
[6]
|
Smith, H.L. (1995) Monotone Dynamical Systems: An Introduction to the Theory of Competitive and Cooperative Systems. Providence, Rhode Island: American Mathematical Society, 41, 81-82.
|
|
[7]
|
Guo, H. (2005) Global Dynamics of a Mathematical Model of Tuberculosis. Canadian Applied Mathematics Quarterly, 13, 313-323.
|
|
[8]
|
Van den Driessche, P. and Watmough, J. (2002) Reproduction Numbers and Sub-Threshold Endemic Equilibria for Compartmental Models of Disease Transmission. Mathematical Biosciences, 180, 29-48. [Google Scholar] [CrossRef]
|
|
[9]
|
La Salle, J.P. (1976) The Stability of Dynamical Systems. SIAM, Philadelphia. [Google Scholar] [CrossRef]
|
|
[10]
|
朱思铭, 王寿松, 李艳会, 等. 常微分方程[M]. 第3版. 北京: 高等教育出版社, 2006.
|