山东人类精子库9520例捐精志愿者精液质量分析

Semen Quality Analysis of 9520 Donors in Shandong Human Sperm Bank

摘要: 目的：回顾性分析山东人类精子库2015年~2019年9520例捐精者初次精液质量，探讨年龄、季节、禁欲天数对精液质量的影响。方法：按年龄分为3组：≤30岁、31~40岁、41~45岁，按季节分为4组：春、夏、秋、冬，按禁欲天数分为3组：3天、4~5天、6~7天。分别对志愿者精液进行体积、精子浓度、活力(a + b)%、精子总数基本参数的检测。采用统计学方法比较各组间是否存在显著性差异。结果：各年龄段间体积比较无显著性差异P = 0.299 (P > 0.05)，各年龄段间精子浓度、(a + b)%、精子总数比较均有显著性差异(P < 0.05)，精液体积、精子浓度、精子总数31~40岁年龄段最高，(a + b)% ≤ 30岁年龄段最高。不同季节各质量参数间比较均有显著性差异(P < 0.05)，各项参数在春季时最高。不同禁欲天数间精液体积、精子浓度、精子总数比较均有显著性差异(P < 0.05)，(a + b)%虽禁欲4~5天时最高，但无显著性差异P = 0.374 (P > 0.05)。结论：综合考虑，捐精志愿者在40岁之前，春季，禁欲4~5天时的精液质量较好。

Abstract: Objective: The first sperm quality of 9520 volunteers in Shandong human sperm bank from 2015 to 2019 was analyzed retrospectively, and the effects of age, season and abstinent days on sperm quality were discussed. Methods: According to the age, they were divided into three groups: 30 years old, 31 - 40 years old, and 41 - 45 years old. According to the season, they were divided into four groups: spring, summer, autumn and winter. According to the days of abstinence, they were divided into three groups: 3 days, 4 - 5 days, and 6 - 7 days. The sperm volume, density, active sperm rate (a + b)% and sums were measured. Statistical methods were used to compare whether there were significant differences between these groups. Results: Volunteers in different ages are not positively correlated to volume (P = 0.299) (P > 0.05). There were significant difference in the sperm density, active sperm rate (a + b)%, and sums among different age groups (P < 0.05). The sperm volume, density and sums were the highest between the ages of 31 and 40, and active sperm rate is the highest under the age of 30. There were significant differences among the quality parameters in different seasons (P < 0.05), and the parameters were the highest in spring. There were significant differences in sperm volume, density and sums among different abstinent days (P < 0.05) (a + b)%. Although sperm quality was the highest between the abstinent days of 4 and 5, there was no significant difference (P = 0.374) (P > 0.05). Conclusion: In conclusion, volunteers under the age of 40 whose sperm quality is the best when they are inhibit sexuality lasts for 4 or 5 days in spring.