无配体钯催化水相Suzuki偶联反应
The Ligand-Free Palladium Catalyzed Suzuki Reaction in Water
DOI: 10.12677/HJCET.2020.104037, PDF,   
作者: 郭 金*, 赵国利, 王少军, 凌凤香：中国石油化工股份有限公司大连石油化工研究院，辽宁 大连；谢以民：山东天力能源股份有限公司，山东 济南
关键词: Suzuki反应；无配体；水相反应；联苯化合物；Suzuki Reaction； Ligand-Free； Aqueous Reaction； Biaryl Compounds
摘要: 建立了水相中无配体钯催化芳基硼酸与溴代芳烃的Suzuki芳基偶联反应体系。该体系以醋酸钯为催化剂，三乙胺为碱，水为溶剂，无需加入任何配体，在100℃下能够有效催化各种芳基硼酸与溴代芳烃的Suzuki偶联反应，底物容忍性好，产品分离收率最高达93%。
Abstract: This paper explores a palladium-catalyzed Suzuki-Miyaura cross-coupling reaction system of arylbromides and arylboronic acids without using any ligands. Using Pd(OAc)2 as catalyst, Et3N as base in water, various aryl bromides could be efficiently coupled with aryl boronic acids, with the excellent product yield up to 93%.
文章引用：郭金, 谢以民, 赵国利, 王少军, 凌凤香. 无配体钯催化水相Suzuki偶联反应[J]. 化学工程与技术, 2020, 10(4): 293-298. https://doi.org/10.12677/HJCET.2020.104037

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