青岛大学附属医院COVID-19患者临床特点及治疗分析

Clinical Characteristics and Treatment of COVID-19 Patients in the Affiliated Hospital of Qingdao University

摘要: 目的：2019年12月，新型冠状病毒肺炎疫情(Coronavirus Disease 2019)在中国爆发。本研究的目的是让临床医生更深入地了解这种新的传染病。方法：收集青岛大学附属医院收治的23例COVID-19患者的流行病学、临床特征、实验室检查、影像学特征、治疗及临床转归等资料进行分析。结果：共纳入23例COVID-19住院患者，中位年龄为43.0岁(IQR 31-57)，没有显著的性别差异(56.5%的女性)，大多数患者有武汉旅居史，大多数患者的胸部CT显示双侧斑片状影或磨玻璃样影。所有患者均接受了抗病毒治疗和糖皮质激素(8例[40%])。除1例死亡病例，1例患者还在住院外，21例患者均已出院，平均住院日为14.52天。结论：本文对23例COVID-19患者的临床特点及治疗方法进行了研究，目前尚无治疗COVID-19的有效抗病毒药物，应避免盲目或不恰当使用抗菌药物，仍需要进一步的临床试验来证实激素的临床益处。

Abstract: Objective: In December 2019, COVID-19 broke out in China. The purpose of this study is to provide clinicians with a better understanding of this new infectious disease. Methods: The data of epidemiology, clinical features, laboratory examination, imaging features, treatment and clinical outcomes of 23 patients admitted to the affiliated hospital of Qingdao university were collected and analyzed. Results: A total of 23 COVID-19 in patients were enrolled. The median age was 43.0 years (IQR 31-57), with no significant gender difference (56.5% of women). Most of the patients had a history of sojourn in Wuhan. Most patients have bilateral patchy or ground-glass images on chest CT. All patients received antiviral therapy and glucocorticoids (8 cases [40%]). In addition to one death and one patient in hospital, all 21 patients were discharged with an average length of stay of 14.52 days. Conclusion: In this study, the clinical characteristics and treatment of 23 COVID-19 patients were studied. Currently, there are no effective antiviral drugs for COVID-19. Blind or inappropriate use of antimicrobial drugs should be avoided.