CDC与WHO新型冠状病毒核酸检测引物比较
Comparison of 2019-nCoV Nucleic Acid Detection Primers between CDC and WHO
DOI: 10.12677/OJNS.2020.84036, PDF,   
作者: 马季荣：浙江师范大学，化学与生命科学学院，浙江 金华
关键词: 2019新型冠状病毒；核酸检测引物；病毒变异；2019-nCoV； Nucleic Acid Detection Primer； Virus Mutation
摘要: 新型冠状病毒(2019-nCoV)引发的人新型冠状病毒性肺炎在全球流行，疫情在中国境内已基本控制，防控重点由诊治确诊患者转向筛查无症状感染者以及严防境外输入病例。目前中国疾病预防控制中心(CDC)与世界卫生组织(WHO)各推荐两对不同的2019-nCoV核酸检测引物，核酸检测引物作为实时荧光RT-PCR病毒核酸检测的关键，面对病毒具有变异速度极快的特点，其灵敏度是否能适应境外2019-nCoV的迅速变异变得尤为重要。
Abstract: Human new coronavirus pneumonia caused by the novel coronavirus (2019-nCoV) is epidemic in the world. The epidemic has been basically controlled in China. The key points of prevention and control are shifted from diagnosis and treatment towards patients to the screening of asymptomatic infected persons and the prevention of imported cases. At present, Chinese Center for Disease Control and Prevention (CDC) and the World Health Organization (WHO) recommend two different pairs of 2019-ncov nucleic acid detection primers. As the key of real-time fluorescent RT-PCR virus nucleic acid detection, nucleic acid detection primers have the characteristics of rapid mutation speed, so it is particularly important about whether their sensitivity can adapt to the rapid mutation of 2019-ncov abroad.
文章引用：马季荣. CDC与WHO新型冠状病毒核酸检测引物比较[J]. 自然科学, 2020, 8(4): 268-272. https://doi.org/10.12677/OJNS.2020.84036

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