超早期颅骨修复改善颅脑损伤患者生活质量的临床研究

Clinical Study on the Improvement of Living Quality in Patients with Craniocerebral Injury by Super Early Cranial Repair

摘要: 目的：颅脑损伤具有较高的致残率和死亡率。颅骨成形术时机的选择对患者的术后的生活质量有重要影响。本文旨在探讨超早期颅骨修补术后患者的生活质量的情况。方法：前瞻性纳入2017年1月至2020年1月共有60例患者在严重颅脑外伤手术后接受了颅骨成形术。根据颅脑损伤术后修复时间将所有患者分为超早期组和常规组。记录性别、年龄、术后KPS评分、ZPS评分、心理功能评分和生活质量评分。结果：KPS评分(p = 0.001)、ZPS评分(p = 0.001)、心理功能评分(p = 0.001)、生活质量评分(p = 0.036)与干预时间显著相关。KPS评分(OR = 0.106, 95% CI: 0.027~0.423, p = 0.001)、ZPS评分(OR = 0.106, 95% CI: 0.027~0.423, p = 0.001)、心理功能评分(OR = 0.149, 95% CI: 0.045~0.492, p = 0.002)、生活质量评分(OR = 0.280, 95% CI: 0.085~0.921, p = 0.036)与患者是否超早期治疗有明显相关性。结论：超早期颅骨修复可提高术后KPS、ZPS评分、心理功能、生活质量评分。

Abstract: Purpose: Craniocerebral injury has a high disability and mortality rate. The choice of the appropriate timing of cranioplasty has an important impact on the prognosis of patients. Therefore, the paper aims to compare the function prognosis between super early repair and conventional repair. Methods: A total of 60 patients who underwent cranioplasty surgery after severe craniocerebral trauma surgery were included in a prospective study between January 2017 and January 2020. All patients were divided into two groups according to the time of cranial repair after operation of craniocerebral injury: super early group and regular group. Sex, age, KPS score, ZPS score, psychological function score and life quality score were recorded. Results: KPS score (p = 0.001), ZPS score (p = 0.001), psychological function score (p = 0.001), and life quality score (p = 0.036) were significantly related to the intervention period. And KPS score (OR = 0.106, 95% CI: 0.027~0423, p = 0.001), ZPS score (OR = 0.106, 95% CI: 0.027~0.423, p = 0.001), psychological function score (OR = 0.149, 95% CI: 0.045~0.492, p = 0.002), and life quality score (OR = 0.280, 95% CI: 0.085~0.921, p = 0.036) have a clear correlation with whether the patients have super early treatment. Conclusion: Super early cranial repair could improve postoperative KPS, ZPS scores, psychological function, and quality of life scores. It can also effectively improve prognosis of patients.