黑磷纳米片层的制备方法及其在生物医学领域的应用
Preparation of Black Phosphorus Nanosheets Layer and Its Application in Biomedical Field
DOI: 10.12677/MS.2020.108080, PDF,   
作者: 李景果, 韩奉奇：河南省人民医院，河南 郑州；郑州大学人民医院，河南 郑州；郑州大学材料科学与工程学院，河南 郑州
关键词: 黑磷；二维材料；光热治疗；光动力治疗；药物载体；生物医学应用；Black Phosphorus； 2D Materials； Photothermal Therapy； Photodynamic Therapy； Drug Delivery； Biomedical Applications
摘要: 黑磷(Black Phosphorus, BP)是一种新型的二维材料，由于其独特、优异的性能，越来越受到研究者的关注。黑磷的能带间隙随层数的变化而变化，且具有高的比表面积、优良的生物相容性和生物可降解性。这些优异的性能使黑磷在生物应用领域具备了无限的潜力，如在光热治疗(photothermal therapy, PTT)、光动力治疗(photodynamic therapy, PDT)、药物载体等方面。相较于其他二维材料，黑磷全部由磷元素构成，当黑磷被应用于体内时可以有效避免人体内部发生免疫反应并有效减少诱发毒性的可能性。虽然黑磷具备广阔的应用前景，但是黑磷在空气中极度不稳定且容易被氧化而失效，该性能严重限制了黑磷的应用。本文不仅总结了黑磷纳米片层的制备方法及如何防止黑磷纳米片层氧化的方法，而且对黑磷在生物医学方面应用的研究进展和未来的发展前景进行了综述和展望。
Abstract: Black Phosphorus (BP), a new 2D material that owns many unique and excellent properties, has gained increased attention in the past years. In particular, its layer-dependent bandgap, large surface-area-to-volume ratio, biodegradability and biocompatibility make it an ideal candidate for photothermal therapy, photodynamic therapy and drug delivery. Compared to other 2D materials, BP is constituted by Phosphorus (P), which is required by the human body and thus it is expected to be biocompatible after suitable engineering of its formulations. Although black phosphorus has many advantages, it’s surface instability due to chemical degradation, which hinders its application. This review not only provides a comprehensive summary on BP preparation and biomedical ap-plications but also looking forward the future possibilities.
文章引用：李景果, 韩奉奇. 黑磷纳米片层的制备方法及其在生物医学领域的应用[J]. 材料科学, 2020, 10(8): 655-667. https://doi.org/10.12677/MS.2020.108080

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