外阴原发性乳腺癌1例报告附文献复习
Primary Breast Cancer of Vulva: A Case Report with Reviewing the Literature
DOI: 10.12677/ACM.2020.109330, PDF,   
作者: 罗 琰*, 江晓虹*, 何信佳, 于 丽, 朱莉金, 贾清玉, 崔欢亮, 赵园园#:青岛大学附属医院肿瘤放疗科,山东 青岛
关键词: 外阴癌乳腺型诊断治疗Vulvar Cancer Breast Diagnosis Treatment
摘要: 目的:报告1例罕见的外阴原发性乳腺癌并结合文献讨论其诊断及治疗方法。方法:以病例报告的方式,结合国外文献复习,综合分析外阴原发性乳腺癌的诊断及治疗。结果:外阴原发性乳腺癌的诊断主要以组织病理学为依据,以手术治疗、化疗、放疗、内分泌治疗、靶向治疗或免疫治疗为主要治疗方法。结论:外阴原发性乳腺癌的诊断需排除外阴转移性乳腺癌及其他外阴原发疾病,以手术治疗为主,根据组织病理学特性选择合适的辅助治疗。
Abstract: Objective: To report a rare case of vulvar primary breast cancer and discuss its diagnosis and treatment combined with literature. Methods: The diagnosis and treatment of vulvar primary breast cancer were analyzed by case report and review of foreign literature. Results: The diagnosis of vulvar primary breast cancer was mainly based on histopathology, and the main treatment was surgical treatment, chemotherapy, radiotherapy, endocrine treatment, targeted treatment or immunotherapy. Conclusion: The diagnosis of vulvar primary breast cancer needs to exclude the metastatic breast cancer and other vulvar primary diseases. The main treatment is surgery, and the appropriate adjuvant treatment is selected according to the histopathological characteristics.
文章引用:罗琰, 江晓虹, 何信佳, 于丽, 朱莉金, 贾清玉, 崔欢亮, 赵园园. 外阴原发性乳腺癌1例报告附文献复习[J]. 临床医学进展, 2020, 10(9): 2185-2188. https://doi.org/10.12677/ACM.2020.109330

参考文献

[1] Fracchioli, S., Puopolo, M., De La Longrais, I.A., Scozzafava, M., Bogliatto, F., Arisio, R., Micheletti, L. and Katsaros, D. (2006) Primary “Breast-Like” Cancer of the Vulva: A Case Report and Critical Review of the Literature. International Journal of Gynecological Cancer: Official Journal of the International Gynecological Cancer Society, 423-428.
[2] Grossl, N. (2000) Supernumerary Breast Tissue: Historical Perspectives and Clinical Features. Southern Medical Journal, 93, 29-32. [Google Scholar] [CrossRef
[3] Simon, K.E., Dutcher, J.P., Runowicz, C.D. and Wiernik, P.H. (1988) Adenocarcinoma Arising in Vulvar Breast Tissue. Cancer, 62, 2234-2238. [Google Scholar] [CrossRef
[4] Lopes, A., Louis, J.St., Balancin, M.L., Barbosa, E.M., Costa, R.L.R., et al. (2018) A Rare Presentation of Primary Breast Carcinoma in the Vulva: A Case Report and Literature Review. Clinical Breast Cancer, 18, e291-e294. [Google Scholar] [CrossRef] [PubMed]
[5] Yang, Z., Li, N., Li, X., Lei, L. and Wang, X. (2020) The Prognostic Impact of Hormonal Receptor and HER-2 Expression Discordance in Metastatic Breast Cancer Patients. OncoTargets and Therapy, 13, 853-863. [Google Scholar] [CrossRef
[6] Vinay, D.S. and Kwon, B.S. (2018) Harnessing Immune Checkpoints for Cancer Therapy. Immunotherapy, 10, 1265-1284. [Google Scholar] [CrossRef] [PubMed]
[7] Ribas, A. and Wolchok, J.D. (2018) Cancer Immunotherapy Using Checkpoint Blockade. Science (New York, NY), 359, 1350-1355. [Google Scholar] [CrossRef] [PubMed]
[8] Wei, P.C., Duffy, C.R. and Allison, J.P. (2018) Fundamental Mechanisms of Immune Checkpoint Blockade Therapy. Cancer Discovery, 8, 1069-1086. [Google Scholar] [CrossRef
[9] Marra, A., Viale, G. and Curigliano, G. (2019) Recent Advances in Triple Negative Breast Cancer: The Immunotherapy Era. BMC Medicine, 17, 90. [Google Scholar] [CrossRef] [PubMed]
[10] Schmid, P., Rugo, H.S., Adams, S., Schneeweiss, A., et al. (2018) Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer. The New England Journal of Medicine, 379, 2108-2121.
[11] Schmid, P., Rugo, H.S., Adams, S., Schneeweiss, A., et al. (2020) Atezolizumab Plus Nab-Paclitaxel as First-Line Treatment for Unresectable, Locally Advanced or Metastatic Triple-Negative Breast Cancer (IMpassion130): Updated Efficacy Results from a Randomised, Double-Blind, Placebo-Controlled, Phase 3 Trial. The Lancet Oncology, 21, 44-59.
[12] Intra, M., Maggioni, A., Sonzogni, A., DE Cicco, C., Machado, L.S., Sagona, A. and Talakhadze, N. (2006) A Rare Association of Synchronous Intraductal Carcinoma of the Breast and Invasive Carcinoma of Ectopic Breast Tissue of the Vulva: Case Report and Literature Review. International Journal of Gynecological Cancer: Official Journal of the International Gynecological Cancer Society, 428-433.