亚甲蓝引起皮肤坏死的一例报告

A Case of Methylene Blue Causing Skin Necrosis

摘要: 乳腺癌前哨淋巴结活检对于部分乳腺癌患者避免了腋窝淋巴结清扫，减少了腋窝淋巴结清扫引起上肢水肿等并发症的发生。亚甲蓝作为一种染料用于前哨淋巴结活检中，具有较高的检出率，但较少文献报道亚甲蓝有引起皮肤坏死的不良反应，本文报道1例亚甲蓝引起皮肤坏死的病例，指导亚甲蓝的规范使用。

Abstract: Sentinel lymph node biopsy of breast cancer avoided axillary lymph node dissection in some breast cancer patients and reduced the incidence of complications such as upper limb edema caused by axillary lymph node dissection. Methylene blue, as a dye used in sentinel lymph node biopsy, has a high detection rate, but less literature reports that methylene blue has adverse reactions that cause skin necrosis. This article reports a case of methylene blue causing skin necrosis, guiding the standardized use of methylene blue.