纳米氧化锌的体内分布以及安全性研究进展
Research Progress on Vivo Distribution and Safety of Nano-Sized Zinc Oxide
DOI: 10.12677/AAC.2020.104016, PDF,   
作者: 段罗艳, 刘天龙*：中国农业大学动物医学院，北京；包汇慧：国家食品安全风险评估中心，北京
关键词: 纳米氧化锌；体内过程；毒性效应；研究进展；ZnO NPs； Vivo Process； Toxic Effect； Research Progress
摘要: 随着纳米技术领域的迅速发展，纳米材料的消费产品及其工业应用也不断增加，目前，纳米产品已经被广泛应用于诊断、食品、化妆品、油漆等领域。其中，由于纳米氧化锌具有良好的抗菌、抗紫外线、耐热以及除臭等特性，它已经被广泛应用于农业、抗癌药物的生产以及食品包装材料。正是由于纳米氧化锌在这些领域中的应用，增加了氧化锌暴露于机体的机会。本文综述了纳米氧化锌经过各种途径作用于机体后的吸收、分布、代谢和排泄等体内过程，并介绍了纳米氧化锌的毒性效应。以期为纳米氧化锌的研究与应用提供参考。
Abstract: With the rapid promotion of nanotechnology, the application of nanomaterials in consumer products and industrial has been increased as well. Nowadays, nanomaterials have been widely applied in areas involving diagnosis, food, cosmetics, paint and so forth. Due to the excellent property of ZnO NPs, such as good antibacterial, anti-ultraviolet, heat resistance and deodorization, it has been extensively exerted in agriculture, the production of anticancer drugs and food packaging materials. However, it is the common application of ZnO NPs in these fields that has increased the risk of human being exposed to ZnO NPs. Therefore, this paper reviewed not only the process of absorption, distribution, metabolism and excretion, but also the toxic effects after exposing ZnO NPs to the all kinds of experimental animals in various ways. It is our expectation that this article could provide reference for the future research and application of ZnO NPs.
文章引用：段罗艳, 包汇慧, 刘天龙. 纳米氧化锌的体内分布以及安全性研究进展[J]. 分析化学进展, 2020, 10(4): 107-114. https://doi.org/10.12677/AAC.2020.104016

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