基于动态网络的蛋白质复合物识别研究综述
Review of Computational Method for Protein Complex Identification Based on Dynamic PPI Networks
DOI: 10.12677/CSA.2020.1012256, PDF,    科研立项经费支持
作者: 于 杨, 孔德宙：沈阳师范大学软件学院，辽宁 沈阳
关键词: 动态网络；复合物识别；基因表达；聚类；Dynamic Network； Protein Complex Identification； Gene Expression； Clustering
摘要: 真实细胞系统中蛋白质及其相互作用是随时变化的，具有一定的动态性。构建蛋白质–蛋白质相互作用(PPI)动态网络并识别蛋白质复合物是揭示细胞功能关键问题。本文介绍了近年来基于动态网路的复合物识别的研究方法，分析了此类复合物预测方法所面临的挑战。
Abstract: In real cell system, proteins and their interactions are always changing and dynamic. It is one of key issues to constructing (PPI) dynamic network and to identify protein complexes for understanding cell function. We summarize the research methods of identification based on dynamic network in recent years, and analyze the challenges in this field.
文章引用：于杨, 孔德宙. 基于动态网络的蛋白质复合物识别研究综述[J]. 计算机科学与应用, 2020, 10(12): 2419-2424. https://doi.org/10.12677/CSA.2020.1012256

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