虚拟支气管镜导航联合超声定位在鞘管引导肺活检中的应用

Application of Virtual Bronchoscopy Navigation Combined with Ultrasound Localization in Sheath Guided Lung Biopsy

摘要: 目的：探究利用虚拟支气管镜导航联合超声定位在鞘管引导肺活检中的应用效果，以期为临床上肺结节的诊断提供新的思路和方法。方法：本研究为回顾性病例对照研究，以自2017年1月1日~2019年6月1日入我院呼吸内科进行肺活检患者为研究对象，共89例，按照是否采用VBN系统分成2组，即VBN组42例和非VBN组47例。统计并记录两组患者的一般资料：包括性别、年龄、病变大小、病变部位和肿瘤类型等，操作时间和癌变诊断率以及术后并发症等，包括喉头水肿、气胸、术后肺部出血、感染、窒息和支气管痉挛。结果：非VBN组患者和VBN组患者的一般基准资料，比如年龄，性别，心功能分级，病变大小和病变部位等比较无统计学意义(P > 0.05)。两组患者的良性结节和恶性肿瘤类型方面无统计学差异(P > 0.05)。非VBN组患者气管镜的操作时间为(923.11 ± 108.57) s，VBN组患者气管镜的操作时间为(588.09 ± 99.43) s，两组患者的气管镜操作时间比较有统计学差异(t = 0.075, P = 0.013 < 0.05)。非VBN组患者的术后喉头水肿、气胸、术后肺部出血、感染、窒息和支气管痉挛的发生率要明显高于VBN组(P < 0.05)。结论：探究利用虚拟支气管镜导航联合超声定位鞘管引导肺活检可以提高肿瘤的检出率，值得进一步推广和应用。

Abstract: Objective: To explore the application effect of virtual bronchoscope navigation combined with ul-trasound localization in sheath guided lung biopsy, so as to provide new ideas and methods for clinical diagnosis of pulmonary nodules. Methods: This study was a retrospective case-control study. A total of 89 patients with lung biopsy admitted to the Department of respiratory medicine of our hospital from January 1, 2017 to June 1, 2019 were selected as the research objects. According to whether VBN system was used or not, they were divided into two groups: 42 cases in VBN group and 47 cases in non VBN group. The general data of the patients in the two groups were statistically recorded, including gender, age, lesion size, lesion location and tumor type, operation time, diagnosis rate of canceration and postoperative complications, including laryngeal edema, pneumothorax, postoperative pulmonary hemorrhage, infection, asphyxia and bronchospasm. Results: There was no significant difference between the non VBN group and the VBN group in general baseline data, such as age, gender, cardiac function classification, lesion size and lesion location (P > 0.05). There was no significant difference in benign nodules and malignant tumor types between the two groups (P > 0.05). The operating time of tracheoscopy was (923.11 ± 108.57) s in non VBN group and (588.09 ± 99.43) s in VBN group. There was significant difference between the two groups (t = 0.075, P = 0.013 < 0.05). The incidence of postoperative laryngeal edema, pneumothorax, postoperative pulmonary hemorrhage, infection, asphyxia and bronchospasm in non VBN group were significantly higher than those in VBN group (P < 0.05). Conclusion: Tvirtual bronchoscope navigation combined with ultrasound guided lung biopsy can improve the detection rate of tumor, which is worthy of further promotion and application.