男性乳腺包裹性乳头状癌3例报道并文献复习

Encapsulated Papillary Carcinoma of the Male Breast: Three Case Reports and Review of the Literature

摘要: 目的：乳腺包裹性乳头状癌(Encapsulated papillary carcinoma, EPC)在男性中极为罕见，对其诊断和治疗了解较少。通过探讨3例男性EPC患者的诊断、治疗及预后，旨在为该疾病的规范诊治提供参考。方法：采用病例报道的方式，结合国内外文献，分析3例患者的诊断、治疗及预后。结果：3例男性患者均经乳房肿块切除活检确诊后行手术治疗，术后均行内分泌治疗，随访23~99个月，无复发及转移。结论：男性乳腺EPC是一种极为少见的低度恶性肿瘤，术前诊断仍依赖乳房肿块切除活检，治疗原则可参照女性，以手术治疗为主，预后较好。

Abstract: Objective: Encapsulated papillary breast carcinoma is extremely rare in males and its diagnosis and treatment are poorly understood. The diagnosis, treatment and prognosis of 3 male EPC patients were discussed in order to provide reference for the standard diagnosis and treatment of this disease. Methods: The diagnosis, treatment and prognosis of 3 patients were analyzed in the form of case reports and combined with review of foreign literature. Results: All the 3 male patients received surgical treatment after the diagnosis of lumpectomy and biopsy, and received endocrine therapy after the operation. The patients were followed up for 23~99 months without recurrence or metastasis. Conclusion: Male breast EPC is a rare low-grade malignant tumor, preoperative diagnosis still depends on lumpectomy and biopsy, and the treatment principle can be referred to women. Surgical treatment is the main treatment with a favorable prognosis.