前列腺癌放射性粒子植入后并发溃疡性结肠炎1例并文献复习
Ulcerative Colitis after Implantation of Radioactive Seeds for Prostate Cancer: A Case Report
DOI: 10.12677/ACM.2021.111012, PDF,   
作者: 李 彬, 姜 波, 宋诗璋, 姜良慧, 侯四川：青岛大学附属青岛市立医院，山东 青岛；韩雪阳：青岛大学附属医院，山东 青岛
关键词: 前列腺癌；近距离放射治疗；炎症性肠病；雄激素剥夺治疗；Prostate Cancer； Brachytherapy； Ulcerative Colitis； Androgen Deprivation Therapy
摘要: 回顾分析我院1例前列腺癌(prostatic cancer, PC)放射性粒子(125I)植入后并发溃疡性结肠炎(ulcerative colitis, UC)患者的临床资料，加强对PC放射性粒子植入后便血的理解与认识。PC放射性粒子植入术后出现腹泻、便血时，我们应该意识到除了放射性结肠炎，还有UC的可能，应行结肠镜检查，早诊断，早治疗。
Abstract: The clinicopathological data of a patient with ulcerative colitis (UC) after implantation of prostatic cancer (PC) radioactive seeds (125I) in our hospital were retrospectively analyzed, to strengthen the understanding of blood in the stool after PC radioactive seeds implantation. When diarrhea and blood in the stool occur after PC radioactive seed implantation, we should be aware of the possibility of UC in addition to radiation colitis. Colonoscopy should be performed for early diagnosis and early treatment.
文章引用：李彬, 韩雪阳, 姜波, 宋诗璋, 姜良慧, 侯四川. 前列腺癌放射性粒子植入后并发溃疡性结肠炎1例并文献复习[J]. 临床医学进展, 2021, 11(1): 87-91. https://doi.org/10.12677/ACM.2021.111012

参考文献

[1] Kim, J. and Feagins, L.A. (2020) Managing Patients with Inflammatory Bowel Disease Who Develop Prostate Cancer. Digestive Diseases and Sciences, 65, 22-30. [Google Scholar] [CrossRef] [PubMed]
[2] Mohammed, W., Hoskin, P., Henry, A., Gomez-Iturriaga, A., Robinson, A. and Nikapota, A. (2018) Short-Term Toxicity of High Dose Rate Brachytherapy in Prostate Cancer Patients with Inflammatory Bowel Disease. Clinical Oncology, 30, 534-538. [Google Scholar] [CrossRef] [PubMed]
[3] Feagins, L.A., Kim, J., Chandrakumaran, A., Gandle, C., Naik, K.H., Cipher, D.J., et al. (2020) Rates of Adverse IBD-Related Outcomes for Patients With IBD and Concomitant Prostate Cancer Treated with Radiation Therapy. Inflammatory Bowel Diseases, 26, 728-733. [Google Scholar] [CrossRef] [PubMed]
[4] Gestaut, M.M. and Swanson, G.P. (2017) Long Term Clinical Toxicity of Radiation Therapy in Prostate Cancer Patients with Inflammatory Bowel Disease. Reports of Practical Oncology & Radiotherapy, 22, 77-82. [Google Scholar] [CrossRef] [PubMed]
[5] Litwin, M.S. and Tan, H.J. (2017) The Diagnosis and Treatment of Prostate Cancer: A Review. JAMA, 317, 2532-2542.
[6] Yao, P., Cui, M., Wang, H., Gao, H., Wang, L., Yang, T., et al. (2016) Quantitative Analysis of Intestinal Flora of Uygur and Han Ethnic Chinese Patients with Ulcerative Colitis. Gastroenterology Research and Practice, 2016, Article ID: 9186232. [Google Scholar] [CrossRef] [PubMed]
[7] Khan, I., Ullah, N., Zha, L., Bai, Y.R., Khan, A., Zhao, T., et al. (2019) Alteration of Gut Microbiota in Inflammatory Bowel Disease (IBD): Cause or Consequence? IBD Treatment Targeting the Gut Microbiome. Pathogens, 8, 126. [Google Scholar] [CrossRef] [PubMed]
[8] Shen, Z.H., Zhu, C.X., Quan, Y.S., Yang, Z.Y., Wu, S., Luo, W.W., et al. (2018) Relationship between Intestinal Microbiota and Ulcerative Colitis: Mechanisms and Clinical Application of Probiotics and Fecal Microbiota Transplantation. World Journal of Gastroenterology, 24, 5-14. http://dx.doi.org/10.3748/wjg.v24.i1.5 [Google Scholar] [CrossRef] [PubMed]
[9] Schroeder, B.O. (2019) Fight Them or Feed Them: How the Intestinal Mucus Layer Manages the Gut Microbiota. Gastroenterology Report, 7, 3-12. [Google Scholar] [CrossRef] [PubMed]
[10] Flier, S.N., Tanjore, H., Kokkotou, E.G., Sugimoto, H., Zeisberg, M. and Kalluri, R. (2010) Identification of Epithelial to Mesenchymal Transition as a Novel Source of Fibroblasts in Intestinal Fibrosis. The Journal of Biological Chemistry, 285, 20202-20212. [Google Scholar] [CrossRef] 
[11] Burns, J.A., Weiner, A.B., Catalona, W.J., Li, E.V., Schaeffer, E.M., Hanauer, S.B., et al. (2019) Inflammatory Bowel Disease and the Risk of Prostate Cancer. European Urology, 75, 846-852. [Google Scholar] [CrossRef] [PubMed]
[12] Mosher, C.A., Brown, G.R., Weideman, R.A., Crook, T.W., Cipher, D.J., Spechler, S.J., et al. (2018) Incidence of Colorectal Cancer and Extracolonic Cancers in Veteran Patients with Inflammatory Bowel Disease. Inflammatory Bowel Diseases, 24, 617-623. [Google Scholar] [CrossRef] [PubMed]
[13] So, J., Tang, W., Leung, W.K., Li, M., Lo, F.H., Wong, M.T.L., et al. (2017) Cancer Risk in 2621 Chinese Patients with Inflammatory Bowel Disease: A Population-Based Cohort Study. Inflammatory Bowel Diseases, 23, 2061-2068. [Google Scholar] [CrossRef] 
[14] Sfanos, K.S., Yegnasubramanian, S., Nelson, W.G. and De Marzo, A.M. (2018) The Inflammatory Microenvironment and Microbiome in Prostate Cancer Development. Nature Reviews Urology, 15, 11-24. [Google Scholar] [CrossRef] [PubMed]
[15] Annede, P., Seisen, T., Klotz, C., Mazeron, R., Maroun, P., Petit, C., et al. (2017) Inflammatory Bowel Diseases Activity in Patients Undergoing Pelvic Radiation Therapy. Journal of Gastrointestinal Oncology, 8, 173-179. [Google Scholar] [CrossRef] [PubMed]
[16] Fijak, M. and Meinhardt, A. (2006) The Testis in Immune Privilege. Immunological Reviews, 213, 66-81. [Google Scholar] [CrossRef] 
[17] Hughes, G.C. and Choubey, D. (2014) Modulation of Autoimmune Rheumatic Diseases by Oestrogen and Progesterone. Nature Reviews Rheumatology, 10, 740-751. [Google Scholar] [CrossRef] [PubMed]
[18] Quintero, O.L., Amador-Patarroyo, M.J., Montoya-Ortiz, G., Rojas-Villarraga, A. and Anaya, J.-M. (2012) Autoimmune Disease and Gender: Plausible Mechanisms for the Female Predominance of Autoimmunity. Journal of Autoimmunity, 38, J109-J119. [Google Scholar] [CrossRef] [PubMed]
[19] Beeson, P.B. (1994) Age and Sex Associations of 40 Autoimmune Diseases. The American Journal of Medicine, 96, 457-462. [Google Scholar] [CrossRef] [PubMed]
[20] Khalili, H., Higuchi, L.M., Ananthakrishnan, A.N., Richter, J.M., Feskanich, D., Fuchs, C.S., et al. (2013) Oral Contraceptives, Reproductive Factors and Risk of Inflammatory Bowel Disease. Gut, 62, 1153-1159. http://dx.doi.org/10.1136/gutjnl-2012-302362 [Google Scholar] [CrossRef] [PubMed]

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