扶正化瘀片与多烯磷脂酰胆碱治疗非酒精性脂肪肝的疗效比较

Comparison of the Therapeutic Effect of FuzhengHuayu Tablet and Polyene Phosphatidylcholine on Nonalcoholic Fatty Liver

摘要: 目的：探讨扶正化瘀片与多烯磷脂酰胆碱治疗非酒精性脂肪肝的疗效。方法：本次研究中所纳入的研究对象为我院医治的120例非酒精性脂肪肝患者，选取的时间段为2019年1月至2019年12月，按不同的治疗方式分为对照组(n = 60)与观察组(n = 60)，对照组采用多烯磷脂酰胆碱治疗，观察组采用扶正化瘀片治疗。观察两组患者肝功能变化情况。结果：两组患者治疗前ALT、AST、TBil无明显差异(P > 0.05)，治疗3周、治疗12周后观察组患者GGT指标均明显低于对照组患者(P < 0.05)。两组治疗前后比较BMI值、W/H值，统计学差异明显(P > 0.05)，但治疗后对照组实验组比较无统计学差异(P < 0.05)。实验组、对照组治疗前B型超声积明显高于治疗后(P > 0.05)；两组治疗后比较无明显差异(P < 0.05)。结论：采用扶正化瘀片治疗非酒精性脂肪肝，能明显改善患者的肝功能指标及肝脏组织学评分，疗效确切，值得应用。

Abstract: Objective: To explore the therapeutic effect of FuzhengHuayu tablet and polyene phosphatidylcholine on nonalcoholic fatty liver. Methods: 120 cases of nonalcoholic fatty liver treated in our hospital were included in this study. The selected period was from January 2019 to December 2019. According to different treatment methods, they were divided into the control group (n = 60) and the observation group (n = 60). The control group was treated with polyene phosphatidylcholine, and the observation group was treated with FuzhengHuayu tablet. The changes of liver function in the two groups were observed. Results: There was no significant difference in alt, AST and TBIL between the two groups before treatment (P > 0.05). GGT indexes of observation group were significantly lower than those of control group after 3 weeks and 12 weeks of treatment (P < 0.05). The BMI and W/H of the two groups were compared before and after treatment, the difference was statistically significant (P > 0.05), but there was no statistical difference between the two groups (P < 0.05). The B-mode ultrasound volume of the experimental group and the control group before treatment was significantly higher than that after treatment (P > 0.05); there was no significant difference between the two groups after treatment (P < 0.05). Conclusion: Using FuzhengHuayu tablet to treat nonalcoholic fatty liver can obviously improve the liver function index and liver histology score of patients, the curative effect is accurate, and it is worth applying.