自然妊娠合并自发性卵巢过度刺激综合征1例并文献复习
A Case of Natural Pregnancy with Spontaneous Ovarian Hyperstimulation Syndrome and Literature Review
摘要: 目的：探讨自发性卵巢过度刺激综合征(sOHSS)的病因、临床表现及诊治要点。方法：对1例自然妊娠合并sOHSS患者的临床资料进行回顾分析并文献复习。结果：患者为26岁妊娠期妇女，停经12周，腹胀加重1月，查体右下腹扪及大小约14 cm囊性包块，左下腹扪及大小约10 cm囊性包块，活动欠佳，无压痛。B超示宫腔内见胎儿回声，心管搏动规律，右侧卵巢大小141 × 100 mm，左侧卵巢104 × 64 mm，内均见多个液性暗区。胸部彩超提示右侧胸腔积液。血清甲胎蛋白(AFP)与糖类抗原125 (CA125)升高。临床诊断：自发性卵巢过度刺激综合征。行腹腔镜下双侧卵巢打孔术 + 双侧卵巢楔形切除术，术后感腹胀等症状较前减轻，常规产检复查B超双侧卵巢体积较前减小，并成功足月顺娩1健康女婴。结论：sOHSS发病率较低，早期诊断和治疗可以有效避免严重的母胎并发症。
Abstract: Objective: To discuss the etiology, clinical manifestations, diagnosis and treatment of spontaneous ovarian hyperstimulation syndrome (sOHSS). Methods: The clinical data of a patient with natural pregnancy complicated with sOHSS were retrospectively analyzed and reviewed. Results: The patient was a 26-year-old pregnant woman with menopause for 12 weeks, and abdominal distension for 1 month. Her right lower abdominal palpation and a cystic mass of about 14 cm in size, and left lower abdominal palpation and a cystic mass of about 10 cm in size were examined. She had poor activity and no tenderness. Ultrasound showed that the fetal echo was seen in the uterine cavity, the heart tube beat regularly, the size of the right ovary was 141 * 100 mm, the left ovary was 104 * 64 mm, and multiple dark liquid areas were seen inside. Color Doppler ultrasound on the chest indicates a pleural effusion on the right side. Serum alpha-fetoprotein (AFP) and carbohydrate antigen 125 (CA125) are elevated. Clinical Diagnosis: Spontaneous ovarian hyperstimulation syndrome. Laparoscopic bilateral ovarian perforation + bilateral wedge resection of the ovary were performed, the postoperative symptoms of abdominal distension and other symptoms were alleviated compared with before, and the volume of bilateral ovaries on the routine obstetric review was reduced compared with that before. She gave birth to 1 healthy baby girl smoothly at full term. Conclusion: The incidence of sOHSS is low, and early diagnosis and treatment can effectively avoid serious maternal-fetal complications.
文章引用：刘光辉, 常晓彤, 宋黄贝, 焦玉雪, 黄煜. 自然妊娠合并自发性卵巢过度刺激综合征1例并文献复习[J]. 临床医学进展, 2021, 11(3): 895-900. https://doi.org/10.12677/ACM.2021.113128

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