肠道菌群失调与IgA肾病的联系
Relationship between Intestinal Flora Imbalance and IgA Nephropathy
DOI: 10.12677/ACM.2021.113188, PDF,   
作者: 高 琪*:青海大学研究生院,青海 西宁;梅 峰#:青海大学附属医院,青海 西宁
关键词: IgA肾病肠道菌群失调多聚体IgAIgA Nephropathy Intestinal Flora Imbalance Polymer IgA
摘要: IgA肾病(IgAN)是我国发病率最高的原发性肾小球肾炎,其确切的病因及发病机制迄今尚不明确,随着研究的深入,很多证据表明肠道菌群微生态失调与IgAN发生和发展相关。本文就IgAN的发病机制,肠道菌群的结构、组成,肠道菌群失调在IgAN发生、发展中的作用,通过调节肠道菌群失调对IgAN在治疗效果方面的研究进展综述如下。
Abstract: IgA nephropathy (IgAN) is the primary glomerulonephritis with the highest incidence in China. Its exact etiology and pathogenesis are still unclear, but more and more evidence shows that the imbalance of intestinal flora is closely related to the occurrence and development of IgAN. This article reviews the pathogenesis of IgA nephropathy, the structure and composition of intestinal flora, the role of intestinal flora imbalance in the occurrence and development of IgA nephropathy, and the therapeutic effect of intestinal flora imbalance on IgA nephropathy.
文章引用:高琪, 梅峰. 肠道菌群失调与IgA肾病的联系[J]. 临床医学进展, 2021, 11(3): 1317-1322. https://doi.org/10.12677/ACM.2021.113188

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